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Hyoscyamine vs. Ditropan XL

Hyoscyamine sulfate is an anticholinergic medication used to treat conditions that involve muscle spasms in different parts of the body, including irritable bowel syndrome (IBS), stomach ulcers, and overactive bladder. It comes in several oral forms including immediate-release tablets, extended-release tablets, sublingual tablets, and liquid solutions. You typically take it by mouth 3 to 4 times a day. Some side effects include dry mouth, sleepiness, and dizziness.

• Stomach and intestine problems (e.g., stomach ulcers, stomach cramps, irritable bowel syndrome)
• Control spasms in certain conditions (e.g., overactive bladder)
• Pain from gallstones or kidney stones
• Runny nose
• Relief of certain symptoms (e.g., sweating, salivation, muscle rigidity, tremors) of Parkinson’s disease
• Colic in babies - oral solution only

• Dry mouth
• Trouble urinating
• Constipation
• Blurry vision
• Dry eyes
• Sleepiness
• Dizziness
• Headache
• Flushing
• Heat intolerance

• Dizziness
• Heat intolerance
• Intestinal blockage
• Faster heart rate
• Reduced saliva

Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.

• Overactive bladder
• Incontinence in children due to a neurologic (brain) condition, such as spina bifida

• Dry mouth (up to 71%)
• Dizziness (up to 17%)
• Constipation (up to 15%)
• Sleepiness (up to 14%)
• Nausea (up to 12%)
• Blurry vision (up to 10%)

• Swelling of face, lips, tongue (angioedema)
• Hallucinations, drowsiness, and confusion
• Worsening of other conditions
• Heat exhaustion