Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Oxybutynin (Oxytrol) and vibegron (Gemtesa) are both medications used to treat overactive bladder (OAB). However, they belong to different medication classes. Oxybutynin is an anticholinergic and antimuscarinic medication, while vibegron is a beta-3 adrenergic agonist. Oxybutynin is available in both short-acting and long-acting oral forms, as well as a patch and gel, and can be used in both adults and children. Vibegron is only available as an oral tablet and is not recommended for children. Oxybutynin can cause side effects like dry mouth, dizziness, and constipation, which are more common in older adults. Vibegron has fewer side effects, but can cause headache and cold symptoms. Oxybutynin is available in generic forms, while vibegron is not.
Oxybutynin
Gemtesa
Oxybutynin
Gemtesa
Summary of Ditropan XL vs. Gemtesa
Summary for Urinary antispasmodic
Prescription only
Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.
Summary for Beta-3 adrenergic agonist
Prescription only
Gemtesa is a brand-name medication that's used to treat overactive bladder (OAB) in adults. This includes OAB in people who are taking medications for benign prostatic hyperplasia (BPH). Gemtesa belongs to the drug class called beta-3 adrenergic agonists. The typical dosage is 1 tablet by mouth once per day. Side effects aren't common but can include headache and symptoms of a common cold. There's no generic version available yet.
Indications of Ditropan XL vs. Gemtesa
Indications for
•Overactive bladder
•Incontinence in children due to a neurologic (brain) condition, such as spina bifida