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Topamax vs. Vesicare

Topiramate (Topamax) belongs to the drug class called antiepileptics. It can be used alone or together with other medications to treat certain types of seizures in people 2 years and older. Topiramate (Topamax) can also be used to prevent migraines in people 12 years and older. It comes as immediate-release tablets and sprinkle capsules. The dosage is taken by mouth twice daily. Topiramate (Topamax) has many possible side effects, like weight loss and tingling of the arms and legs. It can also interact with many other medications.

• Seizures (partial-onset, tonic-clonic, or those from Lennox-Gastaut syndrome) in people 2 years and older
• Migraine prevention in people 12 years and older

• "Pins and needles" feeling
• Sleepiness
• Dizziness
• Fatigue
• Low appetite
• Weight loss
• Nervousness
• Depression
• Trouble concentrating
• Trouble remembering things
• Trouble sleeping
• Trouble moving or keeping balance
• Fever
• Mood changes
• Change in taste

• Vision problems
• High body temperature and trouble sweating
• Too much acid in the blood (metabolic acidosis)
• Changes in mood and risk of suicidal thoughts or behavior
• Problems with memory, speech, or coordination
• Sleepiness, tiredness, and lower concentration
• High ammonia levels in the blood
• Serious skin reactions
• Kidney stones
• Risk of seizures if you stop the medication suddenly
• Bone or growth problems in children
• Interaction with other medications
• Harm to an unborn baby

Solifenacin succinate, also known by the brand name Vesicare, is an anticholinergic medication that's used to treating certain bladder problems. The brand-name and generic tablets help treat overactive bladder in adults. A liquid suspension under the brand name Vesicare LS is also available for children with neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem). This medication is taken by mouth once per day. The most common side effects are dry mouth and constipation.

• Overactive bladder in adults - tablets only
• Neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem) in children ages 2 years and older - liquid only

• Dry mouth (up to 28% in adults, 8% in children)
• Constipation (up to 13% in adults, 3% in children)

• Swelling of the face and possible breathing problems (angioedema)
• Side effects related to the nervous system
• Caution in people with digestive system problems
• Caution in people with glaucoma
• QT prolongation (heart rhythm problem)