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Topamax vs. Dantrium

Topiramate (Topamax) belongs to the drug class called antiepileptics. It can be used alone or together with other medications to treat certain types of seizures in people 2 years and older. Topiramate (Topamax) can also be used to prevent migraines in people 12 years and older. It comes as immediate-release tablets and sprinkle capsules. The dosage is taken by mouth twice daily. Topiramate (Topamax) has many possible side effects, like weight loss and tingling of the arms and legs. It can also interact with many other medications.

• Seizures (partial-onset, tonic-clonic, or those from Lennox-Gastaut syndrome) in people 2 years and older
• Migraine prevention in people 12 years and older

• "Pins and needles" feeling
• Sleepiness
• Dizziness
• Fatigue
• Low appetite
• Weight loss
• Nervousness
• Depression
• Trouble concentrating
• Trouble remembering things
• Trouble sleeping
• Trouble moving or keeping balance
• Fever
• Mood changes
• Change in taste

• Vision problems
• High body temperature and trouble sweating
• Too much acid in the blood (metabolic acidosis)
• Changes in mood and risk of suicidal thoughts or behavior
• Problems with memory, speech, or coordination
• Sleepiness, tiredness, and lower concentration
• High ammonia levels in the blood
• Serious skin reactions
• Kidney stones
• Risk of seizures if you stop the medication suddenly
• Bone or growth problems in children
• Interaction with other medications
• Harm to an unborn baby

Dantrolene sodium is a muscle relaxant. Dantrolene (Dantrium) is used for muscle stiffness or spasms (spasticity), including a severe and potentially life-threatening problem in people receiving surgery called malignant hyperthermia. Dantrolene (Dantrium) is taken by mouth, typically 3 to 4 times per day, by adults and children ages 5 years and older. Dantrolene sodium is also available as injections (Ryanodex and Revonto) given in hospital settings. Some side effects of dantrolene (Dantrium) include sleepiness, dizziness, and diarrhea.

• Long-term muscle spasticity from certain nerve-related conditions
• Prevent or lessen the severity of malignant hyperthermia before procedures

• Dizziness
• Sleepiness
• Weakness
• Tiredness
• Fatigue
• Diarrhea

• Liver injury