Head-to-head comparisons of medication uses, side effects, warnings, and more.
Acamprosate (Campral) and Topiramate (Topamax) are both prescription medications, but they are used for different conditions. Acamprosate is primarily used to treat alcohol dependence by reducing cravings, while Topiramate is an antiepileptic used to control seizures and prevent migraines. Acamprosate needs to be taken three times a day, whereas Topiramate can be taken once or twice daily depending on the formulation. Acamprosate is available as a lower-cost generic, and Topiramate also has generic options. Topiramate has a broader range of uses, including different types of seizures and migraine prevention, but it comes with more severe potential side effects like vision problems and high blood acid levels. Acamprosate, on the other hand, is specifically for alcohol dependence and does not cause a reaction if you drink alcohol while taking it. Both medications can cause suicidal thoughts and behavior, so close monitoring is necessary.
Acamprosate is a first-choice medication used to treat alcohol use disorder in adults who've already stopped drinking. It's a N-methyl-D-aspartate (NMDA) receptor modulator that works by balancing chemicals in the brain to minimize the desire to drink. Acamprosate is taken by mouth, typically three times a day. Some common side effects of this medication include diarrhea, trouble sleeping, and nervousness. Brand name Campral has been discontinued; acamprosate is only available as a generic.
Topiramate is a prescription medication that can be used alone or in combination with other medications to treat certain types of seizures. It can also be used to prevent migraines. It comes in immediate-release and extended-release tablets and capsules, as well as a liquid. Topiramate is typically taken by mouth once or twice daily, depending on what formulation you're using. Some forms of topiramate are available as lower-cost generic medications.
Please note: These are common side effects reported by children and adults who took immediate-release topiramate. Frequency of side effects can differ based on your age, as well as the dose and formulation of topiramate you're taking.
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