Topamax vs. Myrbetriq for Migraine and Overactive Bladder: Important Differences and Potential Risks.

Topiramate

(Topamax)

Myrbetriq

(mirabegron)

Summary for Topamax

Prescription only

Topiramate (Topamax) belongs to the drug class called antiepileptics. It can be used alone or together with other medications to treat certain types of seizures in people 2 years and older. Topiramate (Topamax) can also be used to prevent migraines in people 12 years and older. It comes as immediate-release tablets and sprinkle capsules. The dosage is taken by mouth twice daily. Topiramate (Topamax) has many possible side effects, like weight loss and tingling of the arms and legs. It can also interact with many other medications.

Indications for Topamax

Seizures (partial-onset, tonic-clonic, or those from Lennox-Gastaut syndrome) in people 2 years and older
Migraine prevention in people 12 years and older

Pros and Cons for Topamax

Pros

Can take by itself or with other medications to control seizures
An option for preventing migraines
Also available as a sprinkle capsule that you can open and mix contents with soft food (for people who have trouble swallowing pills)
Approved for both adults and children (age depends on the health problem)

Cons

Taken twice a day
Can cause sleepiness and tingling in the arms or legs
Risk of some serious side effects, like eye problems and kidney stones
Interacts with many medications, like birth control pills, warfarin, and divalproex (Depakote)

Common Side Effects for Topamax

"Pins and needles" feeling
Sleepiness
Dizziness
Fatigue
Low appetite
Weight loss
Nervousness
Depression
Trouble concentrating
Trouble remembering things
Trouble sleeping
Trouble moving or keeping balance
Fever
Mood changes
Change in taste

Warnings for Topamax

Vision problems
High body temperature and trouble sweating
Too much acid in the blood (metabolic acidosis)
Changes in mood and risk of suicidal thoughts or behavior
Problems with memory, speech, or coordination
Sleepiness, tiredness, and lower concentration
High ammonia levels in the blood
Serious skin reactions
Kidney stones
Risk of seizures if you stop the medication suddenly
Bone or growth problems in children
Interaction with other medications
Harm to an unborn baby

Summary for Myrbetriq

Prescription only

Myrbetriq (mirabegron) is used to help with overactive bladder (OAB) in adults. It can also treat a bladder problem called neurogenic detrusor overactivity (NDO) in children 3 years and older. It works as a beta-3 adrenergic agonist to help the bladder hold more urine. Myrbetriq (mirabegron) is taken by mouth once a day. It comes as a brand-name or generic extended-release tablet. A solution made from granules of the medication is available for children, but it's brand name only. Side effects include high blood pressure, cold symptoms, and urinary tract infections.

Indications for Myrbetriq

Overactive bladder (OAB) in adults
Neurogenic detrusor overactivity (NDO) in children ages 3 years and older

Pros and Cons for Myrbetriq

Pros

Helps control sudden urges to urinate, leaks, and needing to go too often
Only taken once a day
Causes less side effects like dry mouth than anticholinergics for overactive bladder (like oxybutynin)
Might be safer for older adults than anticholinergics for overactive bladder

Cons

Might raise your blood pressure
Might have trouble fully emptying your bladder if you have a blockage in your bladder or if you also take anticholinergics for bladder control
Not recommended if you have severe kidney or liver problems

Common Side Effects for Myrbetriq

Adults:

High blood pressure (8-11%)
Common cold symptoms (4%)
Urinary tract infection (3-4%)
Headache (2-3%)
Constipation (2%)
Upper respiratory tract infection (2%)

Children:

Urinary tract infection (24%)
Common cold symptoms (6%)
Constipation (5%)
Headache (4%)
Nausea (2%)

Warnings for Myrbetriq

High blood pressure
Risk of having trouble fully emptying the bladder in certain people
Unusual swelling of the face, lips, or throat (angioedema)
Interactions with other medications

Prices with our coupons for Topamax vs. Myrbetriq

Topiramate30 tablets / 25mg

$5.16$5.16

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Mirabegron30 tablets / 50mg

$121.10$237.93

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Topamax vs. Myrbetriq

Topiramate

Myrbetriq

Summary for Topamax

Indications for Topamax

Pros and Cons for Topamax

Pros

Cons

Common Side Effects for Topamax

Warnings for Topamax

Summary for Myrbetriq

Indications for Myrbetriq

Pros and Cons for Myrbetriq

Pros

Cons

Common Side Effects for Myrbetriq

Warnings for Myrbetriq

Prices with our coupons for Topamax vs. Myrbetriq

Compare other Migraine and Overactive Bladder drugs

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Topiramate

Myrbetriq

Summary for Topamax

Indications for Topamax

Pros and Cons for Topamax

Pros

Cons

Common Side Effects for Topamax

Warnings for Topamax

Summary for Myrbetriq

Indications for Myrbetriq

Pros and Cons for Myrbetriq

Pros

Cons

Common Side Effects for Myrbetriq

Warnings for Myrbetriq