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Topamax vs. Myrbetriq

Topiramate (Topamax) belongs to the drug class called antiepileptics. It can be used alone or together with other medications to treat certain types of seizures in people 2 years and older. Topiramate (Topamax) can also be used to prevent migraines in people 12 years and older. It comes as immediate-release tablets and sprinkle capsules. The dosage is taken by mouth twice daily. Topiramate (Topamax) has many possible side effects, like weight loss and tingling of the arms and legs. It can also interact with many other medications.

• Seizures (partial-onset, tonic-clonic, or those from Lennox-Gastaut syndrome) in people 2 years and older
• Migraine prevention in people 12 years and older

• "Pins and needles" feeling
• Sleepiness
• Dizziness
• Fatigue
• Low appetite
• Weight loss
• Nervousness
• Depression
• Trouble concentrating
• Trouble remembering things
• Trouble sleeping
• Trouble moving or keeping balance
• Fever
• Mood changes
• Change in taste

• Vision problems
• High body temperature and trouble sweating
• Too much acid in the blood (metabolic acidosis)
• Changes in mood and risk of suicidal thoughts or behavior
• Problems with memory, speech, or coordination
• Sleepiness, tiredness, and lower concentration
• High ammonia levels in the blood
• Serious skin reactions
• Kidney stones
• Risk of seizures if you stop the medication suddenly
• Bone or growth problems in children
• Interaction with other medications
• Harm to an unborn baby

Myrbetriq (mirabegron) is used to help with overactive bladder (OAB) in adults. It can also treat a bladder problem called neurogenic detrusor overactivity (NDO) in children 3 years and older. It works as a beta-3 adrenergic agonist to help the bladder hold more urine. Myrbetriq (mirabegron) is taken by mouth once a day. It comes as a brand-name or generic extended-release tablet. A solution made from granules of the medication is available for children, but it's brand name only. Side effects include high blood pressure, cold symptoms, and urinary tract infections.

• Overactive bladder (OAB) in adults
• Neurogenic detrusor overactivity (NDO) in children ages 3 years and older

Adults:

• High blood pressure (8-11%)
• Common cold symptoms (4%)
• Urinary tract infection (3-4%)
• Headache (2-3%)
• Constipation (2%)
• Upper respiratory tract infection (2%)

Children:

• Urinary tract infection (24%)
• Common cold symptoms (6%)
• Constipation (5%)
• Headache (4%)
• Nausea (2%)

• High blood pressure
• Risk of having trouble fully emptying the bladder in certain people
• Unusual swelling of the face, lips, or throat (angioedema)
• Interactions with other medications