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Topamax vs. Detrol

Topiramate (Topamax) belongs to the drug class called antiepileptics. It can be used alone or together with other medications to treat certain types of seizures in people 2 years and older. Topiramate (Topamax) can also be used to prevent migraines in people 12 years and older. It comes as immediate-release tablets and sprinkle capsules. The dosage is taken by mouth twice daily. Topiramate (Topamax) has many possible side effects, like weight loss and tingling of the arms and legs. It can also interact with many other medications.

• Seizures (partial-onset, tonic-clonic, or those from Lennox-Gastaut syndrome) in people 2 years and older
• Migraine prevention in people 12 years and older

• "Pins and needles" feeling
• Sleepiness
• Dizziness
• Fatigue
• Low appetite
• Weight loss
• Nervousness
• Depression
• Trouble concentrating
• Trouble remembering things
• Trouble sleeping
• Trouble moving or keeping balance
• Fever
• Mood changes
• Change in taste

• Vision problems
• High body temperature and trouble sweating
• Too much acid in the blood (metabolic acidosis)
• Changes in mood and risk of suicidal thoughts or behavior
• Problems with memory, speech, or coordination
• Sleepiness, tiredness, and lower concentration
• High ammonia levels in the blood
• Serious skin reactions
• Kidney stones
• Risk of seizures if you stop the medication suddenly
• Bone or growth problems in children
• Interaction with other medications
• Harm to an unborn baby

Tolterodine (Detrol) is used to treat overactive bladder (OAB) in adults. It's an anticholinergic medication that helps with bladder control to lessen the need to go to the restroom suddenly or often. The immediate-release tablet (Detrol) is taken by mouth twice a day. There's also an extended-release capsule (Detrol LA) that's taken just once a day. Both formulations come in brand-name and generic-name versions. Tolterodine (Detrol) can commonly cause dry mouth. Other side effects can include headache and constipation.

• Overactive bladder (OAB)

Immediate-release tablets:

• Dry mouth (35%)
• Headache (7%)
• Constipation (7%)
• Stomach pain (5%)
• Dizziness or feeling like you're spinning (5%)

Extended-release capsules:

• Dry mouth (23%)
• Headache (6%)
• Constipation (6%)
• Stomach pain (4%)

• Serious allergic reaction and swelling (angioedema)
• Dizziness and drowsiness
• Caution use in people with narrow-angle glaucoma
• Caution use in people with trouble urinating
• Caution use in people with problems causing gut blockage
• Caution use in people with myasthenia gravis
• Caution use in people with certain heart rhythm problems