Topamax vs. Sanctura for Epilepsy and Overactive Bladder: Important Differences and Potential Risks.

Topiramate

(Topamax)

Trospium

Summary for Topamax

Prescription only

Topiramate (Topamax) belongs to the drug class called antiepileptics. It can be used alone or together with other medications to treat certain types of seizures in people 2 years and older. Topiramate (Topamax) can also be used to prevent migraines in people 12 years and older. It comes as immediate-release tablets and sprinkle capsules. The dosage is taken by mouth twice daily. Topiramate (Topamax) has many possible side effects, like weight loss and tingling of the arms and legs. It can also interact with many other medications.

Indications for Topamax

Seizures (partial-onset, tonic-clonic, or those from Lennox-Gastaut syndrome) in people 2 years and older
Migraine prevention in people 12 years and older

Pros and Cons for Topamax

Pros

Can take by itself or with other medications to control seizures
An option for preventing migraines
Also available as a sprinkle capsule that you can open and mix contents with soft food (for people who have trouble swallowing pills)
Approved for both adults and children (age depends on the health problem)

Cons

Taken twice a day
Can cause sleepiness and tingling in the arms or legs
Risk of some serious side effects, like eye problems and kidney stones
Interacts with many medications, like birth control pills, warfarin, and divalproex (Depakote)

Common Side Effects for Topamax

"Pins and needles" feeling
Sleepiness
Dizziness
Fatigue
Low appetite
Weight loss
Nervousness
Depression
Trouble concentrating
Trouble remembering things
Trouble sleeping
Trouble moving or keeping balance
Fever
Mood changes
Change in taste

Warnings for Topamax

Vision problems
High body temperature and trouble sweating
Too much acid in the blood (metabolic acidosis)
Changes in mood and risk of suicidal thoughts or behavior
Problems with memory, speech, or coordination
Sleepiness, tiredness, and lower concentration
High ammonia levels in the blood
Serious skin reactions
Kidney stones
Risk of seizures if you stop the medication suddenly
Bone or growth problems in children
Interaction with other medications
Harm to an unborn baby

Summary for Sanctura

Prescription only

Trospium chloride is an antimuscarinic medication that's used to treat overactive bladder in adults. It's available as an immediate-release tablet that's taken by mouth twice daily and an extended-release capsule that's taken once daily. The most common side effects are dry mouth and constipation. The brand name Sanctura has been discontinued, but generic trospium is still available.

Indications for Sanctura

Overactive bladder

Pros and Cons for Sanctura

Pros

Works well to lessen how often you feel the urge to go to the bathroom
Choice of immediate-release tablets taken twice daily or extended-release capsules taken once daily
Available as a lower-cost, generic medication

Cons

Must take on an empty stomach
Only available as a pill (no other formulations for people who have trouble swallowing)
Hasn't been studied in children

Common Side Effects for Sanctura

Immediate-release tablets:

Dry mouth (20%)
Constipation (10%)
Headache (4%)

Extended-release capsules:

Dry mouth (11%)
Constipation (9%)

Warnings for Sanctura

Facial swelling and breathing problems
Nervous system side effects
Trouble urinating
Caution in people with stomach problems
Caution in people with glaucoma

Prices with our coupons for Topamax vs. Sanctura

Topiramate30 tablets / 25mg

$5.32$5.32

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Trospium60 tablets / 20mg

$26.73$92.34

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Topamax vs. Sanctura

Topiramate

Trospium

Summary for Topamax

Indications for Topamax

Pros and Cons for Topamax

Pros

Cons

Common Side Effects for Topamax

Warnings for Topamax

Summary for Sanctura

Indications for Sanctura

Pros and Cons for Sanctura

Pros

Cons

Common Side Effects for Sanctura

Warnings for Sanctura

Prices with our coupons for Topamax vs. Sanctura

Compare other Epilepsy and Overactive Bladder drugs

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Topiramate

Trospium

Summary for Topamax

Indications for Topamax

Pros and Cons for Topamax

Pros

Cons

Common Side Effects for Topamax

Warnings for Topamax

Summary for Sanctura

Indications for Sanctura

Pros and Cons for Sanctura

Pros

Cons

Common Side Effects for Sanctura

Warnings for Sanctura