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Trospium Coupon - Trospium 20mg tablet

trospium

Generic Sanctura
Used for Overactive Bladder
Used for Overactive Bladder

Trospium chloride is an antimuscarinic medication that's used to treat overactive bladder in adults. It's available as an immediate-release tablet that's taken by mouth twice daily and an extended-release capsule that's taken once daily. The most common side effects are dry mouth and constipation. The brand name Sanctura has been discontinued, but generic trospium is still available.

Last reviewed on February 14, 2024
basics-icon

What is Trospium?

What is Trospium used for?

How Trospium works

Trospium is an antimuscarinic medication. It's also often called an anticholinergic. This is because antimuscarinics and anticholinergics work very similarly.

Trospium works by blocking a chemical called acetylcholine from attaching to their receptors in your bladder. This causes your bladder muscles to relax. The medication helps you to go to the bathroom less often and have better control of urination.

Are you looking for information on Spiriva (tiotropium) instead?

Drug Facts

Common BrandsSanctura (brand name no longer available)
Drug ClassAntimuscarinic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$140.68(save 78.90%)
GoodRx discount
$29.69
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What are the side effects of Trospium?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Immediate-release tablets:
  • Dry mouth (20%)
  • Constipation (10%)
  • Headache (4%)
Extended-release capsules:
  • Dry mouth (11%)
  • Constipation (9%)

Other Side Effects

  • Stomach pain
  • Fatigue
  • Sleepiness
  • Dizziness
  • Dry eyes
  • Trouble emptying your bladder
  • Urinary tract infection
  • Overheating

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Angioedema (severe swelling): swelling of the face, lips, tongue, or throat; trouble breathing

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bladder pain

bloody or cloudy urine

decrease in the frequency of urination

decrease in urine volume

difficult or burning urination

difficulty in passing urine (dribbling)

frequent urge to urinate

lower back or side pain

painful urination

Less common

Chills

cough

diarrhea

fast, pounding, or irregular heartbeat or pulse

fever

general feeling of discomfort or illness

headache

joint pain

loss of appetite

muscle aches and pains

nausea

runny nose

shivering

sore throat

sweating

trouble sleeping

unusual tiredness or weakness

vomiting

Incidence not known

Blistering, peeling, or loosening of the skin

changes in vision

clammy skin

confusion as to time, place, or person

dark-colored urine

difficulty with swallowing

dizziness

enlarged pupils

fainting

fast or slow heartbeat

hallucinations

hives

holding false beliefs that cannot be changed by fact

increased sensitivity of the eyes to light

increased sweating, possibly with fever or cold

itching

muscle cramps or spasms

muscle stiffness

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

red, irritated eyes

seeing, hearing, or feeling things that are not there

severe chest pain

severe headache

shortness of breath

skin rash

sores, ulcers, or white spots in the mouth or on the lips

stiff or sore neck

tightness in the chest

unusual excitement, nervousness, or restlessness

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

blurred vision

difficulty having a bowel movement (stool)

dry mouth

dry skin

sleepiness or unusual drowsiness

Less common

Acid or sour stomach

belching

bloated or full feeling

dry eyes

excess air or gas in the stomach or intestines

heartburn

indigestion

passing gas

stomach discomfort, upset, or pain

stuffy nose

trouble with urinating

unable to have a bowel movement (stool)

upper stomach pain

Incidence not known

Burning feeling in the chest or stomach

change in taste

dry throat

indigestion

loss of taste

swelling of the abdomen or stomach area

tenderness in the stomach area

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Trospium

thumbs-up

Pros

Works well to lessen how often you feel the urge to go to the bathroom

Choice of immediate-release tablets taken twice daily or extended-release capsules taken once daily

Available as a lower-cost, generic medication

thumbs-down

Cons

Must take on an empty stomach

Only available as a pill (no other formulations for people who have trouble swallowing)

Hasn't been studied in children

pharmacist-tips

Pharmacist tips for Trospium

pharmacist
  • For immediate-release trospium tablets: Take the immediate-release tablet twice per day with water. Take the medication on an empty stomach or at least 1 hour before a meal.

    • For extended-release trospium capsules: Take the extended-release capsule once per day in the morning. Take the capsule on an empty stomach, at least 1 hour before a meal.

      • It's best to avoid alcohol while you're taking trospium because alcohol can worsen side effects like drowsiness. The manufacturer recommends that you wait at least 2 hours after you take the extended-release capsule before you drink any alcohol.

        • Trospium can affect your ability to think, focus, and react. It can also sometimes cause blurry vision. Don't drive, operate machinery, or do anything that you need to concentrate or see clearly for until you know how this medication affects you.

          • Drinking water, especially when it's hot, can also prevent your body from overheating easily. Trospium can cause your body to make less sweat and make you thirstier.

            • Let your healthcare team know if you're pregnant or planning to become pregnant. It's not completely known whether trospium can harm your unborn baby.

              • Tell your primary care provider if you're breastfeeding or planning to nurse. It's not known whether trospium can pass into your breast milk and harm your baby. Your primary care provider can recommend safe options while you're taking trospium.

                faqs

                Frequently asked questions about Trospium

                Does trospium cause weight gain?
                During clinical trials, weight loss or weight gain weren't reported side effects of trospium. Contact your primary care provider if you notice unexpected changes in your weight while you're taking trospium.
                Can you take trospium at night?
                It depends on the formulation of trospium that you're taking. For immediate-release tablets that are typically taken twice daily, you can take the second dose of the day at night. Just make sure you take the medication on an empty stomach or at least 1 hour before dinner. But for extended-release capsules, you should take the medication in the morning. Talk to your healthcare team if taking the extended-release capsules in the morning isn't convenient for you.
                How long does it take for trospium to work?
                Studies show that trospium takes a few days to start improving overactive bladder symptoms. But keep in mind everyone responds differently to medications. Talk to your care team if you're concerned about how well trospium is working for you.
                How long should I take trospium?
                There isn't a set amount of time for how long you need to take trospium. You can continue taking trospium as long as it's helping your overactive bladder symptoms and you're not having any significant side effects. Speak with your primary care provider about how long you should take the medication, how well trospium is working for you, and whether you're having any bothersome side effects.
                Can I just stop taking trospium?
                You shouldn't stop taking trospium without first talking with your healthcare team. Doing so can cause rebound symptoms, such as nausea, sweating, and the urge to urinate more. Work with your care team to come up with a plan for stopping the medication if you want to stop taking trospium.
                Does trospium cause constipation?
                Yes, anticholinergic medications like trospium are known to cause constipation because they slow down the movement of your digestive tract. In clinical trials, about 10% of people who took trospium reported having constipation. You can try to prevent constipation by doing things like eating a high-fiber diet and staying hydrated. And if you become constipated, there are several over-the-counter medications you can try to help relieve this side effect.
                What's the difference between trospium and oxybutynin?
                Both trospium and oxybutynin are anticholinergic medications that can help treat overactive bladder symptoms. They also have similar side effects. Both medications are available as immediate-release and extended-release pills. But there are more formulations of oxybutynin to choose from: an oral liquid, patches placed on the skin, and a gel that's applied on the skin. Studies show that the immediate-release versions of both medications work just as well as each other, but trospium appears to cause less dry mouth as a side effect. Speak with your primary care provider about which medication is right for you.
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                What are the risks and warnings for Trospium?

                Trospium can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Facial swelling and breathing problems

                Some people who took trospium have reported experiencing an uncommon, but serious side effect called angioedema. This involves swelling in different parts of the body, including the face, throat, and tongue. Swelling of the tongue or throat area can be potentially life-threatening, since it can make it hard to breathe. Go to the emergency room right away if you suddenly can't breathe or notice swelling around your face or throat.

                risk-warning

                Nervous system side effects

                Trospium can cause sleepiness, dizziness, and hallucinations (seeing or hearing things that aren't real). Don't drive or do any activity that requires a lot of attention until you know how this medication makes you feel. Let your healthcare team know if you're experiencing any of these side effects and if they affect your usual daily activities. You might need to have your trospium dose lowered.

                risk-warning

                Trouble urinating

                Use trospium with caution if you have prostate problems or other blockage in the urinary tract that makes it hard for you to urinate. Trospium can worsen your problems with urinating.

                risk-warning

                Caution in people with stomach problems

                Trospium can slow the gut down to a stop. This can lead to serious problems, like severe inflammation and swelling of the colon. Let your primary care provider know if you have a history of stomach problems like ulcerative colitis. Also tell your care team if you have any nerve problems like myasthenia gravis; these nerve problems can sometimes affect how well your gut works. Discuss your medical history with your primary care provider to see whether trospium is safe for you.

                risk-warning

                Caution in people with glaucoma

                • Risk factors: Glaucoma

                  Trospium can cause vision changes, like blurry vision or worsening of glaucoma symptoms. Before you start taking trospium, tell your primary care provider if you have glaucoma so they can discuss the risks and benefits of this medication. Also let your ophthalmologist know if you're taking trospium. It's recommended that you get regular eye exams done if you have glaucoma and you're taking trospium.

                  dosage

                  Trospium dosage forms

                  The average cost for 60 tablets of 20mg of Trospium is $29.69 with a free GoodRx coupon. This is 78.9% off the average retail price of $140.68.
                  tablet
                  Tablet
                  DosageQuantityPrice as low asPrice per unit
                  20mg60 tablets$29.69$0.49

                  Typical dosing for Trospium

                  You should take trospium on an empty stomach or at least 1 hour before a meal.

                  Your dose might differ if you have kidney problems or if you're 75 years of age or older.

                  interactions

                  Interactions between Trospium and other drugs

                  Trospium may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Trospium. Please note that only the generic name of each medication is listed below.

                  Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                  • Potassium

                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                  drug-cost

                  How much does Trospium cost?

                  To access savings, use a GoodRx coupon and pay just a fraction of the retail price.View prices & coupons
                  contraindications-icon

                  Trospium contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Trospium will not be safe for you to take.
                  alternatives

                  What are alternatives to Trospium?

                  There are a number of medications that your doctor can prescribe in place of Trospium. Compare a few possible alternatives below.
                  Trospium
                  $29.69 Lowest GoodRx priceView Prices
                  Used for:
                  • Overactive bladder

                  • Incontinence in children due to a neurologic (brain) condition, such as spina bifida

                  $8.50 Lowest GoodRx priceView Prices
                  Used for:
                  $380.63 Lowest GoodRx priceView Prices
                  images

                  Trospium images

                  White Round Pad And 145 - Trospium Chloride 20mg Tablet
                  This medicine is White, Round Tablet Imprinted With "145" And "Pad".White Round Pad And 145 - Trospium Chloride 20mg Tablet
                  White Round Hp And 530 - Trospium Chloride 20mg Tablet
                  This medicine is White, Round Tablet Imprinted With "530" And "Hp".White Round Hp And 530 - Trospium Chloride 20mg Tablet
                  Yellow Round 20 - Trospium Chloride 20mg Tablet
                  This medicine is Yellow, Round Tablet Imprinted With "20".Yellow Round 20 - Trospium Chloride 20mg Tablet
                  Yellow Round Tr 20 And Apo - Trospium Chloride 20mg Tablet
                  This medicine is Yellow, Round Tablet Imprinted With "Tr 20" And "Apo".Yellow Round Tr 20 And Apo - Trospium Chloride 20mg Tablet
                  White Round Hp And 530 - Trospium Chloride 20mg Tablet
                  This medicine is White, Round Tablet Imprinted With "530" And "Hp".White Round Hp And 530 - Trospium Chloride 20mg Tablet
                  Yellow Round 1 And L - Trospium Chloride 20mg Tablet
                  This medicine is Yellow, Round Tablet Imprinted With "L" And "1".Yellow Round 1 And L - Trospium Chloride 20mg Tablet
                  Yellow Round Ig And 336 - Trospium Chloride 20mg Tablet
                  This medicine is Yellow, Round Tablet Imprinted With "Ig" And "336".Yellow Round Ig And 336 - Trospium Chloride 20mg Tablet

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                  References

                  Best studies we found

                  Epstein, B. J., et al. (2006). Newer agents for the management of overactive bladder. American Family Physician.

                  Fernandez, J. (2023). Angioedema. Merck Manual Consumer Version.

                  Glenmark Pharmaceuticals Inc., USA. (2023). Trospium chloride tablet, film coated [package insert]. DailyMed.

                  View All References (6)

                  Gomelsky, A., et al. (2011). OAB update: Focus on trospium. Clinical Medicine Insights: Urology.

                  Howland, R. H. (2010). Potential adverse effects of discontinuing psychotropic drugs. Part 1: Adrenergic, cholinergic, and histamine drugs. Journal of Psychosocial Nursing and Mental Health Services.

                  National Institute of Diabetes and Digestive and Kidney Diseases. (2019). Definition & facts of urinary retention.

                  Sam, C., et al. (2023). Physiology, acetylcholine. StatPearls.

                  Slate Run Pharmaceuticals, LLC. (2024). Trospium chloride capsule, extended release [package insert]. DailyMed.

                  Zinner, N., et al. (2004). Trospium chloride improves overactive bladder symptoms: A multicenter phase III trial. The Journal of Urology.

                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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