Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Vibegron (Gemtesa) and tamsulosin (Flomax) are both oral medications used to address urinary issues, but they belong to different medication classes and have distinct uses. Vibegron is a beta-3 adrenergic agonist primarily used to treat overactive bladder (OAB), including in those taking medications for benign prostatic hyperplasia (BPH). Tamsulosin, on the other hand, is an alpha-1 blocker specifically approved for treating BPH by relaxing muscles in the prostate and bladder to ease urination. Vibegron is taken once daily at a dose of 75 mg, while tamsulosin is typically started at 0.4 mg once daily, taken 30 minutes after the same meal each day. Vibegron is only available as a brand-name medication, whereas tamsulosin is available as a lower-cost generic. Common side effects of vibegron include headache and cold symptoms, while tamsulosin may cause headaches, dizziness, and abnormal ejaculation.
Gemtesa
Tamsulosin
Gemtesa
Tamsulosin
Summary of Gemtesa vs. Flomax
Summary for Beta-3 adrenergic agonist
Prescription only
Gemtesa is a brand-name medication that's used to treat overactive bladder (OAB) in adults. This includes OAB in people who are taking medications for benign prostatic hyperplasia (BPH). Gemtesa belongs to the drug class called beta-3 adrenergic agonists. The typical dosage is 1 tablet by mouth once per day. Side effects aren't common but can include headache and symptoms of a common cold. There's no generic version available yet.
Summary for Alpha-1 blocker
Prescription only
Tamsulosin is an alpha-1 blocker used to treat benign prostatic hyperplasia (BPH), also known as enlarged prostate. It works by relaxing the muscles in your prostate and bladder, making it easier to urinate. The medication comes as a capsule that you take once a day, usually 30 minutes after the same meal each day. Side effects include headache, dizziness, and abnormal ejaculation.