Key takeaways
Oxybutynin ER (Ditropan XL) and Solifenacin (Vesicare) are both medications used to treat overactive bladder (OAB), but they have some differences. Oxybutynin ER is available in both generic and brand forms, while Solifenacin is available as a brand (Vesicare) and generic tablets, but its liquid form (Vesicare LS) is only available as a brand. Oxybutynin ER can be taken in various forms, including tablets, syrup, and solution, whereas Solifenacin is only available as tablets and liquid. Oxybutynin ER is taken 2 to 4 times a day for the short-acting form or once daily for the long-acting form, while Solifenacin is taken once daily. Both medications can cause side effects like dry mouth and dizziness, especially in older adults. Both medications can cause dry mouth and should be used carefully in people with certain conditions like narrow-angle glaucoma and difficulty urinating.
