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Compare Toviaz vs. Vesicare

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Fesoterodine (Toviaz) and solifenacin (Vesicare) are both medications used to treat overactive bladder (OAB), but they have some differences. Fesoterodine (Toviaz) is an anticholinergic urinary antispasmodic that also treats neurogenic detrusor overactivity (NDO) in children, while solifenacin (Vesicare) is an anticholinergic and antimuscarinic that can be used for incontinence in children due to neurological conditions. Fesoterodine (Toviaz) is available as a generic, whereas solifenacin (Vesicare) has a generic form for tablets but not for its liquid version. Both medications are taken once a day, but fesoterodine (Toviaz) is an extended-release tablet, and solifenacin (Vesicare) can be taken as a tablet or liquid. Common side effects for both include dry mouth and constipation, but solifenacin (Vesicare) tends to have milder side effects overall. Additionally, solifenacin (Vesicare) can cause rare but serious heart rhythm problems, which is not noted for fesoterodine (Toviaz).

  • Fesoterodine (Toviaz)
    Solifenacin (Vesicare)
  • Fesoterodine (Toviaz)
    Solifenacin (Vesicare)

  • Summary of Toviaz vs. Vesicare

    Summary for Urinary antispasmodic
    Prescription only

    Fesoterodine fumarate (Toviaz) is an anticholinergic urinary antispasmodic. It relieves symptoms of overactive bladder (OAB) in adults. Brand name Toviaz is also approved to treat neurogenic detrusor overactivity (NDO) in children. Fesoterodine (Toviaz) is an extended-release tablet that's taken by mouth once a day. Some side effects of this medication include dry mouth and constipation.

    Summary for Anticholinergic
    Prescription only

    Solifenacin succinate, also known by the brand name Vesicare, is an anticholinergic medication that's used to treating certain bladder problems. The brand-name and generic tablets help treat overactive bladder in adults. A liquid suspension under the brand name Vesicare LS is also available for children with neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem). This medication is taken by mouth once per day. The most common side effects are dry mouth and constipation.

  • Indications of Toviaz vs. Vesicare

    Indications for
    •Overactive bladder (OAB) in adults
    •Neurogenic detrusor overactivity (NDO) in children ages 6 years and older - brand Toviaz only
    Indications for
    •Overactive bladder in adults - tablets only
    •Neurogenic detrusor overactivity (NDO) (urinary incontinence due to a neurologic problem) in children ages 2 years and older - liquid only

  • Pros and Cons of Toviaz vs. Vesicare

    Pros and Const for Urinary antispasmodic
    Pros
    •Taken by mouth
    •Taken once a day
    •Available as a lower-cost generic
    Cons
    •Interacts with many medications
    •Can cause dry mouth and constipation
    •Can't be used by people with an allergy to tolterodine (Detrol)
    Pros and Const for Anticholinergic
    Pros
    •Only taken once per day, with or without food
    •Comes as a tablet and a liquid suspension
    •Liquid suspension available for children as young as 2 years old
    Cons
    •Commonly causes dry mouth
    •Liquid suspension is brand name only
    •Not a good option for people who have trouble urinating or certain gut problems

  • Common Side Effects of Toviaz vs. Vesicare

    Common Side Effects for

    Adults (OAB)

    •Dry mouth (19-35%)
    •Constipation (4-6%)
    •Urinary tract infection (3-4%)
    •Upper respiratory tract infection (2-3%)
    •Dry eyes (1-4%)

    Children (NDO)

    •Diarrhea (7-12%)
    •Urinary tract infection (2-10%)
    •Dry mouth (7-10%)
    •Constipation (7%)
    Common Side Effects for
    •Dry mouth (up to 28% in adults, 8% in children)
    •Constipation (up to 13% in adults, 3% in children)

  • Warnings of Toviaz vs. Vesicare

    Common Side Effects for
    •Unusual swelling of the face, lips, or throat (angioedema)
    •Trouble urinating and stomach problems
    •Vision changes
    •Dizziness and drowsiness
    •Myasthenia gravis
    Common Side Effects for
    •Swelling of the face and possible breathing problems (angioedema)
    •Side effects related to the nervous system
    •Caution in people with digestive system problems
    •Caution in people with glaucoma
    •QT prolongation (heart rhythm problem)

  • Prices with our coupons for Toviaz vs. Vesicare

    Learn more about Fesoterodine
    Learn more about Solifenacin

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