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Compare Enablex vs. Ditropan XL

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Darifenacin ER (formerly brranded as Enablex) and oxybutynin ER (formerly branded as Ditropan and Ditropan XL) are both used to treat overactive bladder (OAB) but have some differences. Darifenacin is taken once a day and is known for having fewer side effects compared to oxybutynin, making it a better option for some people. Oxybutynin can be taken in both short-acting and long-acting forms, with the long-acting form taken once daily. While both medications can cause dry mouth and constipation, oxybutynin has a higher incidence of these side effects. Additionally, oxybutynin can be used in children as young as 5 years old, whereas darifenacin is not typically used in children. Both medications can cause dizziness and drowsiness, but oxybutynin has a higher risk of causing these side effects, especially in older adults. Lastly, darifenacin is generally not recommended for people over 65, while oxybutynin requires careful dosing in this age group to minimize side effects.

  • Darifenacin
    Oxybutynin
  • Darifenacin
    Oxybutynin

  • Summary of Enablex vs. Ditropan XL

    Summary for Anticholinergic
    Prescription only

    Darifenacin hydrobromide is a medication that treats overactive bladder in adults. It belongs to a drug class called anticholinergics. Darifenacin comes as an extended-release tablet that you take by mouth once a day. Common side effects include dry mouth and constipation. The brand name of the medication, Enablex, has been discontinued. So generic darifenacin is the only version available now.

    Summary for Urinary antispasmodic
    Prescription only

    Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.

  • Indications of Enablex vs. Ditropan XL

    Indications for
    •Overactive bladder (OAB) in adults
    Indications for
    •Overactive bladder
    •Incontinence in children due to a neurologic (brain) condition, such as spina bifida

  • Pros and Cons of Enablex vs. Ditropan XL

    Pros and Const for Anticholinergic
    Pros
    •Helps lower the urge to urinate and improves bladder control
    •Taken by mouth once per day
    Cons
    •Commonly causes dry mouth, which can be uncomfortable
    •Not the best choice for people with severe liver problems, certain gut problems, or trouble urinating
    Pros and Const for Urinary antispasmodic
    Pros
    •Works well to improve symptoms of OAB
    •Available as a convenient, once-daily tablet (Ditropan XL)
    •Can be used in children as young as 5 years old
    •Available as an oral liquid, good for people who have trouble swallowing tablets
    Cons
    •Commonly causes dry mouth as a side effect
    •Higher risk of side effects in people age 65 and older
    •Can cause dizziness and drowsiness
    •Shouldn't be used by people who have untreated narrow-angle glaucoma, difficulty urinating, or movement problems with the stomach or intestines

  • Common Side Effects of Enablex vs. Ditropan XL

    Common Side Effects for
    •Dry mouth (up to 35%)
    •Constipation (up to 21%)
    •Urinary tract infection (5%)
    Common Side Effects for
    •Dry mouth (up to 71%)
    •Dizziness (up to 17%)
    •Constipation (up to 15%)
    •Sleepiness (up to 14%)
    •Nausea (up to 12%)
    •Blurry vision (up to 10%)

  • Warnings of Enablex vs. Ditropan XL

    Common Side Effects for
    •Swelling of the face and possible breathing problems (angioedema)
    •Side effects related to the nervous system
    •Caution in people with blockage in the bladder
    •Caution in people with digestive problems
    •Caution in people with glaucoma
    Common Side Effects for
    •Swelling of face, lips, tongue (angioedema)
    •Hallucinations, drowsiness, and confusion
    •Worsening of other conditions
    •Heat exhaustion

  • Prices with our coupons for Enablex vs. Ditropan XL

    Learn more about Darifenacin
    Learn more about Oxybutynin

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