Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Myrbetriq vs. Sanctura

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Myrbetriq (mirabegron) and trospium (Sanctura) are both used to treat overactive bladder (OAB), but they work in different ways and have different side effects. Myrbetriq is a beta-3 adrenergic agonist that helps your bladder relax so it can hold more urine, and it's taken once daily. Trospium, on the other hand, is an antimuscarinic medication that blocks acetylcholine to relax the bladder muscles, and it comes in both immediate-release tablets taken twice daily and extended-release capsules taken once daily. Myrbetriq can cause high blood pressure and urinary tract infections, while trospium commonly causes dry mouth and constipation. Unlike Myrbetriq, which has no generic version, trospium is available in a generic form. Additionally, Myrbetriq can be taken with or without food, but trospium must be taken on an empty stomach. Both medications can cause serious side effects like angioedema, but trospium also has risks related to vision changes and nervous system effects.

  • Myrbetriq (mirabegron)
    Trospium
  • Myrbetriq (mirabegron)
    Trospium

  • Summary of Myrbetriq vs. Sanctura

    Summary for Beta-3 adrenergic agonist
    Prescription only

    Myrbetriq (mirabegron) is used to help with overactive bladder (OAB) in adults. It can also treat a bladder problem called neurogenic detrusor overactivity (NDO) in children 3 years and older. It works as a beta-3 adrenergic agonist to help the bladder hold more urine. Myrbetriq (mirabegron) is taken by mouth once a day. It comes as a brand-name or generic extended-release tablet. A solution made from granules of the medication is available for children, but it's brand name only. Side effects include high blood pressure, cold symptoms, and urinary tract infections.

    Summary for Antimuscarinic
    Prescription only

    Trospium chloride is an antimuscarinic medication that's used to treat overactive bladder in adults. It's available as an immediate-release tablet that's taken by mouth twice daily and an extended-release capsule that's taken once daily. The most common side effects are dry mouth and constipation. The brand name Sanctura has been discontinued, but generic trospium is still available.

  • Indications of Myrbetriq vs. Sanctura

    Indications for
    •Overactive bladder (OAB) in adults
    •Neurogenic detrusor overactivity (NDO) in children ages 3 years and older
    Indications for
    •Overactive bladder

  • Pros and Cons of Myrbetriq vs. Sanctura

    Pros and Const for Beta-3 adrenergic agonist
    Pros
    •Helps control sudden urges to urinate, leaks, and needing to go too often
    •Only taken once a day
    •Causes less side effects like dry mouth than anticholinergics for overactive bladder (like oxybutynin)
    •Might be safer for older adults than anticholinergics for overactive bladder
    Cons
    •Might raise your blood pressure
    •Might have trouble fully emptying your bladder if you have a blockage in your bladder or if you also take anticholinergics for bladder control
    •Not recommended if you have severe kidney or liver problems
    Pros and Const for Antimuscarinic
    Pros
    •Works well to lessen how often you feel the urge to go to the bathroom
    •Choice of immediate-release tablets taken twice daily or extended-release capsules taken once daily
    •Available as a lower-cost, generic medication
    Cons
    •Must take on an empty stomach
    •Only available as a pill (no other formulations for people who have trouble swallowing)
    •Hasn't been studied in children

  • Common Side Effects of Myrbetriq vs. Sanctura

    Common Side Effects for

    Adults:

    •High blood pressure (8-11%)
    •Common cold symptoms (4%)
    •Urinary tract infection (3-4%)
    •Headache (2-3%)
    •Constipation (2%)
    •Upper respiratory tract infection (2%)

    Children:

    •Urinary tract infection (24%)
    •Common cold symptoms (6%)
    •Constipation (5%)
    •Headache (4%)
    •Nausea (2%)
    Common Side Effects for

    Immediate-release tablets:

    •Dry mouth (20%)
    •Constipation (10%)
    •Headache (4%)

    Extended-release capsules:

    •Dry mouth (11%)
    •Constipation (9%)

  • Warnings of Myrbetriq vs. Sanctura

    Common Side Effects for
    •High blood pressure
    •Risk of having trouble fully emptying the bladder in certain people
    •Unusual swelling of the face, lips, or throat (angioedema)
    •Interactions with other medications
    Common Side Effects for
    •Facial swelling and breathing problems
    •Nervous system side effects
    •Trouble urinating
    •Caution in people with stomach problems
    •Caution in people with glaucoma

  • Prices with our coupons for Myrbetriq vs. Sanctura

    Learn more about Myrbetriq
    Learn more about Trospium

Compare other Overactive Bladder drugs

Enablex vs MyrbetriqGemtesa vs MyrbetriqMyrbetriq vs DetrolMyrbetriq vs DitropanMyrbetriq vs FlomaxMyrbetriq vs OxybutyninMyrbetriq vs SancturaMyrbetriq vs ToviazMyrbetriq vs VesicarePropranolol vs MyrbetriqTopamax vs MyrbetriqDitropan vs VesicareEnablex vs DetrolEnablex vs OxybutyninEnablex vs SancturaEnablex vs ToviazEnablex vs VesicareGemtesa vs FlomaxGemtesa vs SolifenacinGemtesa vs TolterodineGemtesa vs VesicareOxybutynin vs SancturaOxybutynin vs VesicarePropranolol vs SancturaPropranolol vs VesicareSanctura vs ToviazTopamax vs SancturaTopamax vs VesicareToviaz vs VesicareVesicare vs Detrol
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.