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Compare Flomax vs. Rapaflo

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Tamsulosin (Flomax) and silodosin (Rapaflo) are both alpha-1 blockers used to treat symptoms of benign prostatic hyperplasia (BPH), or an enlarged prostate. Tamsulosin is taken 30 minutes after the same meal each day, while silodosin is taken with a meal, and you can open the capsule and sprinkle it on applesauce if you have trouble swallowing. Both medications are available as lower-cost generics. Both medications can cause dizziness and issues with ejaculation, including retrograde ejaculation (orgasm with little or no semen). Tamsulosin has a higher risk of causing a sudden drop in blood pressure when standing up, while silodosin is not suitable for people with severe kidney or liver problems. Both medications interact with many other medications, so you should always check with a healthcare professional before starting any new treatments.

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