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Compare Rapaflo vs. Uroxatral

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Silodosin (Rapaflo) and Alfuzosin (Uroxatral) are both alpha-1 blockers used to treat symptoms of benign prostatic hyperplasia (BPH). Silodosin is available as a capsule, while Alfuzosin comes in an extended-release tablet form. You take Silodosin once daily with a meal, and it can cause side effects like retrograde ejaculation and dizziness. Alfuzosin is also taken once daily after the same meal each day and can cause dizziness and headaches. Unlike Silodosin, Alfuzosin should not be crushed or chewed because it is an extended-release medication. Both medications can lower your blood pressure, but Alfuzosin has a specific warning about causing a painful erection called priapism, which is rare. Additionally, Silodosin is not recommended for people with severe kidney or liver problems, while Alfuzosin should be avoided in those with moderate to severe liver issues. Both medications are available in generic forms, making them more affordable options.

  • Silodosin (Rapaflo)
    Alfuzosin er (Uroxatral)
  • Silodosin (Rapaflo)
    Alfuzosin er (Uroxatral)

  • Summary of Rapaflo vs. Uroxatral

    Summary for Alpha blocker
    Prescription only

    Silodosin (Rapaflo) is used to treat symptoms of benign prostatic hyperplasia (BPH), or having an enlarged prostate. This medication is available as a brand-name and generic version, and it comes as a capsule that you take by mouth. The dosage is typically just once daily with a meal, but it can affect your ejaculation as a side effect (for example, causing you to orgasm with less or no semen).

    Summary for Alpha-1 adrenergic receptor blocker
    Prescription only

    Alfuzosin ER (Uroxatral) is used to treat benign prostatic hyperplasia (BPH) in males. It's taken by mouth only once daily because it's an extended-release (ER) medication. Alfuzosin ER (Uroxatral) is available as generic and brand name tablets. Common side effects of this medication include dizziness and headaches.

  • Indications of Rapaflo vs. Uroxatral

    Indications for
    •Benign prostatic hyperplasia (BPH)
    Indications for
    •Signs and symptoms of benign prostatic hyperplasia (BPH)

  • Pros and Cons of Rapaflo vs. Uroxatral

    Pros and Const for Alpha blocker
    Pros
    •Helps improve symptoms of BPH
    •Once-daily dosing
    •Can open capsules and sprinkle the powder inside on applesauce if it's hard to swallow the capsules whole
    •Lower-cost generic version available
    Cons
    •Has some side effects related to low blood pressure, such as dizziness
    •Can cause retrograde ejaculation (an orgasm with little or no semen), but is reversible when you stop the medication
    •Might complicate cataract surgery
    •Can't use if you have severe kidney or liver problems
    Pros and Const for Alpha-1 adrenergic receptor blocker
    Pros
    •Works to control BPH symptoms
    •Only need to take once daily
    •Taken by mouth
    •Available in a lower-cost, generic form
    Cons
    •Must take with a meal (the same one everyday)
    •Can cause dizziness and headache
    •Can't be used for people with moderate to severe liver problems
    •Interacts with some common medications, such as blood pressure medications

  • Common Side Effects of Rapaflo vs. Uroxatral

    Common Side Effects for
    •Retrograde ejaculation (orgasm with less or no semen; 28%)
    •Dizziness (3%)
    •Diarrhea (3%)
    •Drop in blood pressure when standing from a seated or lying down position (3%)
    Common Side Effects for
    •Dizziness (6%)
    •Upper respiratory tract infection (3%)
    •Headache (3%)
    •Fatigue (3%)

  • Warnings of Rapaflo vs. Uroxatral

    Common Side Effects for
    •Low blood pressure
    •Higher risk for side effects in people with kidney problems
    •Interactions with other medications
    •Should rule out prostate cancer
    •Floppy iris syndrome (a cataract surgery complication)
    Common Side Effects for
    •Drop in blood pressure upon standing
    •Interactions with other medications
    •Caution for people with liver or kidney problems
    •Caution for people with heart problems
    •Painful erection (priapism)
    •Eye problems during surgery

  • Prices with our coupons for Rapaflo vs. Uroxatral

    Learn more about Silodosin
    Learn more about Alfuzosin er

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