Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Doxazosin (Cardura) and dutasteride / tamsulosin (Jalyn) are both medications used to treat symptoms of an enlarged prostate, also known as benign prostatic hyperplasia (BPH). However, they belong to different medication classes and have distinct mechanisms of action. Doxazosin is an alpha-1 blocker that helps relax muscles in the prostate and bladder, while Jalyn combines a 5-alpha reductase inhibitor (dutasteride) and an alpha-1 adrenergic receptor blocker (tamsulosin) to reduce prostate size and relax muscles. Doxazosin is also FDA-approved to treat high blood pressure, but Jalyn is not. Doxazosin is available in immediate-release and extended-release forms, typically taken once a day, while Jalyn is taken as a single capsule daily. Common side effects of doxazosin include dizziness and fatigue, whereas Jalyn may also cause ejaculation problems and a lower sex drive. Both medications can cause a drop in blood pressure upon standing, but Jalyn has additional warnings related to prostate cancer risk.
Doxazosin (Cardura)
Jalyn (dutasteride / tamsulosin)
Doxazosin (Cardura)
Jalyn (dutasteride / tamsulosin)
Summary of Cardura vs. Jalyn
Summary for Alpha antagonist
Prescription only
Doxazosin mesylate (Cardura) is an alpha-1 blocker that's used to treat adults with enlarged prostate (benign prostatic hyperplasia, BPH) or high blood pressure. It's also available as brand name Cardura XL, an extended-release tablet that's FDA approved for treating BPH only. The typical dosage is one tablet by mouth once a day. Side effects include low blood pressure, dizziness, and fatigue.
Summary for 5-alpha reductase inhibitor / Alpha-1 adrenergic receptor blocker
Prescription only
Jalyn (dutasteride / tamsulosin) is a combination medication used to relieve symptoms of enlarged prostate (benign prostatic hyperplasia or BPH). Although it works well, it can cause problems with ejaculation, erection, and your sex drive.