Key takeaways
Terazosin (generic, formerly branded as Hytrin) and Silodosin (generic and branded as Rapaflo) are both alpha-1 blockers used to treat symptoms of benign prostatic hyperplasia (BPH). Terazosin can also be used to treat high blood pressure, while Silodosin is only used for BPH. Terazosin is typically taken once daily at bedtime, whereas Silodosin is taken once daily with a meal. Both medications can cause dizziness and low blood pressure, especially when you stand up quickly, but Silodosin can also cause issues with ejaculation, such as having an orgasm with little or no semen. Both medications can complicate cataract surgery, including the potential for causing a condition called floppy iris syndrome. Additionally, Silodosin should not be used if you have severe kidney or liver problems, while Terazosin does not have this restriction.
