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Compare Hytrin vs. Rapaflo

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Terazosin (generic, formerly branded as Hytrin) and Silodosin (generic and branded as Rapaflo) are both alpha-1 blockers used to treat symptoms of benign prostatic hyperplasia (BPH). Terazosin can also be used to treat high blood pressure, while Silodosin is only used for BPH. Terazosin is typically taken once daily at bedtime, whereas Silodosin is taken once daily with a meal. Both medications can cause dizziness and low blood pressure, especially when you stand up quickly, but Silodosin can also cause issues with ejaculation, such as having an orgasm with little or no semen. Both medications can complicate cataract surgery, including the potential for causing a condition called floppy iris syndrome. Additionally, Silodosin should not be used if you have severe kidney or liver problems, while Terazosin does not have this restriction.

  • Terazosin
    Silodosin (Rapaflo)
  • Terazosin
    Silodosin (Rapaflo)

  • Summary of Hytrin vs. Rapaflo

    Summary for Alpha-1 blocker
    Prescription only

    Terazosin is a medication that’s typically used to treat difficulty urinating caused by an enlarged prostate (also known as benign prostatic hyperplasia or BPH). It can also be used to treat high blood pressure, but it’s not a first-choice option for this condition due to the risk of side effects, like feeling dizzy or weak, particularly for older adults. Terazosin is taken by mouth, typically once daily at bedtime. It’s only available as a lower-cost generic (former brand name Hytrin).

    Summary for Alpha blocker
    Prescription only

    Silodosin (Rapaflo) is used to treat symptoms of benign prostatic hyperplasia (BPH), or having an enlarged prostate. This medication is available as a brand-name and generic version, and it comes as a capsule that you take by mouth. The dosage is typically just once daily with a meal, but it can affect your ejaculation as a side effect (for example, causing you to orgasm with less or no semen).

  • Indications of Hytrin vs. Rapaflo

    Indications for
    •Difficulty urinating caused by an enlarged prostate (benign prostatic hyperplasia, BPH)
    •High blood pressure
    Indications for
    •Benign prostatic hyperplasia (BPH)

  • Pros and Cons of Hytrin vs. Rapaflo

    Pros and Const for Alpha-1 blocker
    Pros
    •Available as a lower-cost generic medication
    •Taken once a day
    •Can be taken with or without food
    Cons
    •Not a first-choice option for high blood pressure
    •Can cause dizziness, especially if you stand up quickly
    •If you miss your dose for many days, you may need to restart treatment at the starting dose
    Pros and Const for Alpha blocker
    Pros
    •Helps improve symptoms of BPH
    •Once-daily dosing
    •Can open capsules and sprinkle the powder inside on applesauce if it's hard to swallow the capsules whole
    •Lower-cost generic version available
    Cons
    •Has some side effects related to low blood pressure, such as dizziness
    •Can cause retrograde ejaculation (an orgasm with little or no semen), but is reversible when you stop the medication
    •Might complicate cataract surgery
    •Can't use if you have severe kidney or liver problems

  • Common Side Effects of Hytrin vs. Rapaflo

    Common Side Effects for

    Benign prostatic hyperplasia (BPH):

    •Dizziness (9%)
    •Weakness (7%)

    High blood pressure:

    •Dizziness (19%)
    •Headache (16%)
    •Weakness (11%)
    Common Side Effects for
    •Retrograde ejaculation (orgasm with less or no semen; 28%)
    •Dizziness (3%)
    •Diarrhea (3%)
    •Drop in blood pressure when standing from a seated or lying down position (3%)

  • Warnings of Hytrin vs. Rapaflo

    Common Side Effects for
    •Dangerously low blood pressure and risk of fainting
    •Painful erection (priapism)
    •Eye problems during surgery
    Common Side Effects for
    •Low blood pressure
    •Higher risk for side effects in people with kidney problems
    •Interactions with other medications
    •Should rule out prostate cancer
    •Floppy iris syndrome (a cataract surgery complication)

  • Prices with our coupons for Hytrin vs. Rapaflo

    Learn more about Terazosin
    Learn more about Silodosin

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