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Compare Enablex vs. Myrbetriq

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Darifenacin ER (formerly branded as Enablex) and Myrbetriq (mirabegron) are both used to treat overactive bladder (OAB) symptoms, but they work in different ways and have distinct characteristics. Darifenacin ER is a urinary antispasmodic that relaxes bladder muscles by blocking certain receptors, while Myrbetriq is a beta-3 adrenergic agonist that helps the bladder hold more urine by activating specific proteins. Darifenacin ER and Myrbetriq are both available in generic forms, making them more cost-effective option. Myrbetriq can be used in children aged 3 and older for neurogenic detrusor overactivity (NDO), while darifenacin ER is only for adults. Common side effects of darifenacin ER include dry mouth and constipation, whereas Myrbetriq can cause high blood pressure and urinary tract infections. Additionally, darifenacin ER is generally not recommended for those 65 or older due to increased risk of dizziness and drowsiness, while Myrbetriq might be safer for older adults.

  • Darifenacin
    Myrbetriq (mirabegron)
  • Darifenacin
    Myrbetriq (mirabegron)

  • Summary of Enablex vs. Myrbetriq

    Summary for Anticholinergic
    Prescription only

    Darifenacin hydrobromide is a medication that treats overactive bladder in adults. It belongs to a drug class called anticholinergics. Darifenacin comes as an extended-release tablet that you take by mouth once a day. Common side effects include dry mouth and constipation. The brand name of the medication, Enablex, has been discontinued. So generic darifenacin is the only version available now.

    Summary for Beta-3 adrenergic agonist
    Prescription only

    Myrbetriq (mirabegron) is used to help with overactive bladder (OAB) in adults. It can also treat a bladder problem called neurogenic detrusor overactivity (NDO) in children 3 years and older. It works as a beta-3 adrenergic agonist to help the bladder hold more urine. Myrbetriq (mirabegron) is taken by mouth once a day. It comes as a brand-name or generic extended-release tablet. A solution made from granules of the medication is available for children, but it's brand name only. Side effects include high blood pressure, cold symptoms, and urinary tract infections.

  • Indications of Enablex vs. Myrbetriq

    Indications for
    •Overactive bladder (OAB) in adults
    Indications for
    •Overactive bladder (OAB) in adults
    •Neurogenic detrusor overactivity (NDO) in children ages 3 years and older

  • Pros and Cons of Enablex vs. Myrbetriq

    Pros and Const for Anticholinergic
    Pros
    •Helps lower the urge to urinate and improves bladder control
    •Taken by mouth once per day
    Cons
    •Commonly causes dry mouth, which can be uncomfortable
    •Not the best choice for people with severe liver problems, certain gut problems, or trouble urinating
    Pros and Const for Beta-3 adrenergic agonist
    Pros
    •Helps control sudden urges to urinate, leaks, and needing to go too often
    •Only taken once a day
    •Causes less side effects like dry mouth than anticholinergics for overactive bladder (like oxybutynin)
    •Might be safer for older adults than anticholinergics for overactive bladder
    Cons
    •Might raise your blood pressure
    •Might have trouble fully emptying your bladder if you have a blockage in your bladder or if you also take anticholinergics for bladder control
    •Not recommended if you have severe kidney or liver problems

  • Common Side Effects of Enablex vs. Myrbetriq

    Common Side Effects for
    •Dry mouth (up to 35%)
    •Constipation (up to 21%)
    •Urinary tract infection (5%)
    Common Side Effects for

    Adults:

    •High blood pressure (8-11%)
    •Common cold symptoms (4%)
    •Urinary tract infection (3-4%)
    •Headache (2-3%)
    •Constipation (2%)
    •Upper respiratory tract infection (2%)

    Children:

    •Urinary tract infection (24%)
    •Common cold symptoms (6%)
    •Constipation (5%)
    •Headache (4%)
    •Nausea (2%)

  • Warnings of Enablex vs. Myrbetriq

    Common Side Effects for
    •Swelling of the face and possible breathing problems (angioedema)
    •Side effects related to the nervous system
    •Caution in people with blockage in the bladder
    •Caution in people with digestive problems
    •Caution in people with glaucoma
    Common Side Effects for
    •High blood pressure
    •Risk of having trouble fully emptying the bladder in certain people
    •Unusual swelling of the face, lips, or throat (angioedema)
    •Interactions with other medications

  • Prices with our coupons for Enablex vs. Myrbetriq

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    Learn more about Myrbetriq

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