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Compare Ditropan XL vs. Sanctura

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Oxybutynin ER (Ditropan XL) and trospium are both used to treat overactive bladder (OAB), but they have some differences. Oxybutynin ER is available in more forms, including tablets, oral liquid, patches, and gel, while trospium is only available as a pill. Both medications can cause dry mouth and constipation, but trospium tends to cause less dry mouth. Oxybutynin ER can be used in children as young as 5 years old, whereas trospium hasn't been studied in children. You need to take trospium on an empty stomach, but you can take oxybutynin ER with or without food. Both medications can cause dizziness and drowsiness.

  • Oxybutynin
    Trospium
  • Oxybutynin
    Trospium

  • Summary of Ditropan XL vs. Sanctura

    Summary for Urinary antispasmodic
    Prescription only

    Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.

    Summary for Antimuscarinic
    Prescription only

    Trospium chloride is an antimuscarinic medication that's used to treat overactive bladder in adults. It's available as an immediate-release tablet that's taken by mouth twice daily and an extended-release capsule that's taken once daily. The most common side effects are dry mouth and constipation. The brand name Sanctura has been discontinued, but generic trospium is still available.

  • Indications of Ditropan XL vs. Sanctura

    Indications for
    •Overactive bladder
    •Incontinence in children due to a neurologic (brain) condition, such as spina bifida
    Indications for
    •Overactive bladder

  • Pros and Cons of Ditropan XL vs. Sanctura

    Pros and Const for Urinary antispasmodic
    Pros
    •Works well to improve symptoms of OAB
    •Available as a convenient, once-daily tablet (Ditropan XL)
    •Can be used in children as young as 5 years old
    •Available as an oral liquid, good for people who have trouble swallowing tablets
    Cons
    •Commonly causes dry mouth as a side effect
    •Higher risk of side effects in people age 65 and older
    •Can cause dizziness and drowsiness
    •Shouldn't be used by people who have untreated narrow-angle glaucoma, difficulty urinating, or movement problems with the stomach or intestines
    Pros and Const for Antimuscarinic
    Pros
    •Works well to lessen how often you feel the urge to go to the bathroom
    •Choice of immediate-release tablets taken twice daily or extended-release capsules taken once daily
    •Available as a lower-cost, generic medication
    Cons
    •Must take on an empty stomach
    •Only available as a pill (no other formulations for people who have trouble swallowing)
    •Hasn't been studied in children

  • Common Side Effects of Ditropan XL vs. Sanctura

    Common Side Effects for
    •Dry mouth (up to 71%)
    •Dizziness (up to 17%)
    •Constipation (up to 15%)
    •Sleepiness (up to 14%)
    •Nausea (up to 12%)
    •Blurry vision (up to 10%)
    Common Side Effects for

    Immediate-release tablets:

    •Dry mouth (20%)
    •Constipation (10%)
    •Headache (4%)

    Extended-release capsules:

    •Dry mouth (11%)
    •Constipation (9%)

  • Warnings of Ditropan XL vs. Sanctura

    Common Side Effects for
    •Swelling of face, lips, tongue (angioedema)
    •Hallucinations, drowsiness, and confusion
    •Worsening of other conditions
    •Heat exhaustion
    Common Side Effects for
    •Facial swelling and breathing problems
    •Nervous system side effects
    •Trouble urinating
    •Caution in people with stomach problems
    •Caution in people with glaucoma

  • Prices with our coupons for Ditropan XL vs. Sanctura

    Learn more about Oxybutynin
    Learn more about Trospium

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