Gemtesa is a brand-name medication that's used to treat overactive bladder (OAB) in adults. This includes OAB in people who are taking medications for benign prostatic hyperplasia (BPH). Gemtesa belongs to the drug class called beta-3 adrenergic agonists. The typical dosage is 1 tablet by mouth once per day. Side effects aren't common but can include headache and symptoms of a common cold. There's no generic version available yet.
Gemtesa is a beta-3 adrenergic agonist. It turns on a protein in your bladder called beta-3 adrenergic receptor. This causes your bladder muscles to relax so that your bladder can hold more urine. It helps lessen the need to go to the bathroom as often.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Gemtesa can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Angioedema (swelling of the face, lips, tongue, throat, or other organs) can happen at any time while you're taking Gemtesa. In more serious cases, swelling of the throat can make it difficult to breathe, which can be life-threatening. Talk to your care team if you have any head or neck swelling that doesn't go away. Get medical help right away if you have serious swelling or difficulty breathing.
Some people who took Gemtesa had problems urinating or emptying their bladder completely. The risk might be higher if you have a blockage in your bladder or if you take anticholinergic medications for overactive bladder. Keeping urine in your bladder for long periods of time can lead to complications, such as urinary tract infection (UTI) bladder damage, and kidney damage. Let your prescriber know if you can't urinate or can't empty your bladder fully, even though you feel the urge to urinate.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 75mg | 30 tablets | $493.02 | $16.43 |
The typical dose is 75 mg by mouth once per day.
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Gemtesa can start to work in as early as 2 weeks. But it can take about 3 months to get the full effects of the medication. Talk to your prescriber if you have concerns about how long it takes for Gemtesa to work.
It can take about 6 days for most of Gemtesa to leave your body after a single dose. This time frame is estimated based on the half-life of the medication. But even though the medication can stay in your system for about 6 days, you should still take it once every day. This helps keep the levels of Gemtesa high enough in your body to work well.
People who've previously had a severe allergic reaction to Gemtesa shouldn't take it. A severe allergic reaction can include swelling of the face or mouth or trouble breathing. In addition, speak with your prescriber first if you're taking mirabegron (Myrbetriq). Mirabegron (Myrbetriq) and Gemtesa belong to the same drug class, and taking them together might raise your risk for side effects. Also talk to your prescriber about whether you should continue taking Gemtesa if you have bothersome side effects from the medication.
Dry eyes isn't a typical side effect of Gemtesa. If you have dry eyes, you can try artificial tears. Contact your optometrist or ophthalmologist (eye specialist) if your dry eyes get too bothersome.
Hair loss wasn't a side effect that people who took Gemtesa reported in clinical trials. Contact your prescriber if you notice unusual hair loss while you're taking Gemtesa. They can examine what's causing this hair loss.
No. People who took Gemtesa during clinical trials didn't report having fatigue or tiredness. Speak with your primary care provider if you feel unusually tired while you're taking this medication.
No, Gemtesa doesn't typically cause weight gain. Let your primary care provider know if you experience unexpected weight gain. They can help figure out the cause.
Tell your healthcare team if you're pregnant or breastfeeding. They can discuss with you about the risks and benefits of taking Gemtesa. It's not clear whether this medication is safe for you and your baby. But animal studies show that it isn't expected to cause harm to babies.