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Compare Robinul vs. Ditropan XL

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Glycopyrrolate (Robinul) and Oxybutynin ER (Ditropan XL) are both anticholinergic medications, but they are used for different conditions. Glycopyrrolate is primarily used as an add-on treatment for stomach ulcers, while Oxybutynin ER is used to treat overactive bladder (OAB). Glycopyrrolate is available in both oral tablet and orally disintegrating tablet forms, whereas Oxybutynin ER comes in extended-release tablets, as well as short-acting tablets, oral syrup, and oral solution. Glycopyrrolate is taken two to three times daily, while Oxybutynin ER is typically taken once daily. Both medications can cause dry mouth, constipation, and dizziness, blurred vision, and sleepiness. Oxybutynin ER is not recommended for people with untreated narrow-angle glaucoma, difficulty urinating, or certain stomach and intestine problems, while Glycopyrrolate is not recommended for those with glaucoma, blocked urine flow, or stomach blockage.

  • Glycopyrrolate (Robinul)
    Oxybutynin
  • Glycopyrrolate (Robinul)
    Oxybutynin

  • Summary of Robinul vs. Ditropan XL

    Summary for Anticholinergic
    Prescription only

    Glycopyrrolate (Robinul) is used with other medications to treat stomach ulcers. It's not as commonly used anymore due to newer available treatments and many unpleasant side effects. Glycopyrrolate is also available as Dartisla ODT, a tablet that dissolves when you put it on top of your tongue.

    Summary for Urinary antispasmodic
    Prescription only

    Oxybutynin is used to treat overactive bladder (OAB). Oral oxybutynin is available as a short-acting tablet and solution that is taken 2 to 4 times a day. It also comes as a long-acting tablet that's taken once daily (brand name Ditropan XL). Some common side effects of oxybutynin include dry mouth, constipation, and dizziness. Older adults typically lower doses of this medication to lower the risk for side effects.

  • Indications of Robinul vs. Ditropan XL

    Indications for
    •Add-on treatment for stomach ulcers
    Indications for
    •Overactive bladder
    •Incontinence in children due to a neurologic (brain) condition, such as spina bifida

  • Pros and Cons of Robinul vs. Ditropan XL

    Pros and Const for Anticholinergic
    Pros
    •Oral tablet is available in generic form
    •Oral tablet comes in different strengths
    •Also available as an orally disintegrating tablet (Dartisla ODT) for people who have trouble swallowing pills
    Cons
    •Works only as an add-on treatment, so you have to take other medications with it
    •Has many undesirable side effects such as dry mouth, difficulty urinating, and sleepiness
    •Not recommended for older adults since it can raise the risk of side effects
    Pros and Const for Urinary antispasmodic
    Pros
    •Works well to improve symptoms of OAB
    •Available as a convenient, once-daily tablet (Ditropan XL)
    •Can be used in children as young as 5 years old
    •Available as an oral liquid, good for people who have trouble swallowing tablets
    Cons
    •Commonly causes dry mouth as a side effect
    •Higher risk of side effects in people age 65 and older
    •Can cause dizziness and drowsiness
    •Shouldn't be used by people who have untreated narrow-angle glaucoma, difficulty urinating, or movement problems with the stomach or intestines

  • Common Side Effects of Robinul vs. Ditropan XL

    Common Side Effects for
    •Dry mouth
    •Less sweating
    •Difficulty urinating
    •Constipation
    •Nausea
    •Vomiting
    •Feeling bloated
    Common Side Effects for
    •Dry mouth (up to 71%)
    •Dizziness (up to 17%)
    •Constipation (up to 15%)
    •Sleepiness (up to 14%)
    •Nausea (up to 12%)
    •Blurry vision (up to 10%)

  • Warnings of Robinul vs. Ditropan XL

    Common Side Effects for
    •Worsening glaucoma
    •Heat stroke or fever
    •Stomach blockage
    •Drowsiness and blurred vision
    •Worsening of other health conditions
    Common Side Effects for
    •Swelling of face, lips, tongue (angioedema)
    •Hallucinations, drowsiness, and confusion
    •Worsening of other conditions
    •Heat exhaustion

  • Prices with our coupons for Robinul vs. Ditropan XL

    Learn more about Glycopyrrolate
    Learn more about Oxybutynin

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