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Glycopyrrolate Coupon - Glycopyrrolate 1mg tablet

glycopyrrolate

Generic Robinul
Used for Anesthesia, Peptic Ulcer, Salivation
Used for Anesthesia, Peptic Ulcer, Salivation

Glycopyrrolate (Robinul) is used with other medications to treat stomach ulcers. It's not as commonly used anymore due to newer available treatments and many unpleasant side effects. Glycopyrrolate is also available as Dartisla ODT, a tablet that dissolves when you put it on top of your tongue.

Reviewed by:
reviewer
Shifali Patel, PharmD
reviewer
Daisy Chau, PharmD
Last reviewed on February 5, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsImagesReferencesPricesMedicare
basics-icon

What is Glycopyrrolate (Robinul)?

What is Glycopyrrolate (Robinul) used for?

  • Add-on treatment for stomach ulcers

How Glycopyrrolate (Robinul) works

Glycopyrrolate (Robinul) belongs to a group of medications known as anticholinergics, which block a chemical in our body called acetylcholine. By blocking acetylcholine, glycopyrrolate (Robinul) lowers the amount of acid in your stomach and helps to relieve symptoms of stomach ulcers.

Are you looking for information on Cuvposa (glycopyrrolate) oral solution or Lonhala (glycopyrrolate) inhalation solution instead?

Drug Facts

Common BrandsRobinul, Robinul Forte, Glycate
Drug ClassAnticholinergic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$69.73(save 82.79%)
GoodRx discount
$12.00
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What are the side effects of Glycopyrrolate (Robinul)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dry mouth
  • Less sweating
  • Difficulty urinating
  • Constipation
  • Nausea
  • Vomiting
  • Feeling bloated

Other Side Effects

  • Vision changes or blurred vision
  • Higher heart rate
  • Loss of taste
  • Headache
  • Dizziness
  • Confusion
  • Nervousness
  • Sleepiness
  • Problems sleeping (insomnia)
  • Unable to get an erection (impotence)
  • Less breast milk production

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Worsening glaucoma: dilated pupils with eye pain or redness
  • Toxic megacolon: stomach pain, stomach swelling or bloating, fever, bloody diarrhea, fast heartbeat, confusion

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Body aches or pain

chills

constipation

cough

decrease in the frequency of urination

decrease in urine volume

difficulty in passing urine (dribbling)

difficulty with breathing

ear congestion

feeling of warmth

fever

headache

loss of voice

nasal congestion

painful urination

redness of the face, neck, arms, and occasionally, upper chest

runny nose

sneezing

sore throat

unusual tiredness or weakness

Less common

Abdominal or stomach discomfort or pain

abdominal or stomach distension

chest pain

confusion

convulsions

dizziness

dry heaves

dry mouth

fainting

increase in heart rate

lightheadedness

pain or tenderness around the eyes and cheekbones

rapid breathing

shortness of breath or troubled breathing

stuffy nose

sunken eyes

thirst

tightness in the chest

vomiting

wheezing

wrinkled skin

Get emergency help immediately if any of the following symptoms of overdose occur:

low blood pressure

muscle weakness

trouble breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Altered mood

anxiety

attack, assault, or force

bloated

change in taste

chapped lips

crying

dry skin

dry tongue

excess air or gas in the stomach or intestines

full feeling

hyperventilation

irregular heartbeats

irritability

loss of taste

moaning

nervousness

pain

paleness of the skin

passing gas

rash

restlessness

shaking

trouble with sleeping

uncontrolled eye movements

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Glycopyrrolate (Robinul)

thumbs-up

Pros

Oral tablet is available in generic form

Oral tablet comes in different strengths

Also available as an orally disintegrating tablet (Dartisla ODT) for people who have trouble swallowing pills

thumbs-down

Cons

Works only as an add-on treatment, so you have to take other medications with it

Has many undesirable side effects such as dry mouth, difficulty urinating, and sleepiness

Not recommended for older adults since it can raise the risk of side effects

pharmacist-tips

Pharmacist tips for Glycopyrrolate (Robinul)

pharmacist

  • If you're taking glycopyrrolate (Robinul) tablets, you can take them with or without food. But if you're taking Dartisla ODT, make sure you take it on an empty stomach. This means at least 1 hour before or 2 hours after food.

    • When taking Dartisla ODT, place the tablet on top of your tongue and let it dissolve on its own. Once it's dissolved, swallow without drinking any water.

      • Glycopyrrolate (Robinul) can lower your body's ability to sweat, which is what your body does when it gets too hot. Be careful when you're exercising or in hot weather while taking this medication. This can raise your risk of having a fever and heat stroke.

        • Don't drive or do anything that requires you to be alert while taking glycopyrrolate (Robinul) before knowing how the medication affects you as it can cause sleepiness and blurry vision.

          • Glycopyrrolate (Robinul) can cause dry mouth. Sipping water, chewing gum, sucking on hard candies or ice cubes, or using over-the-counter (OTC) saliva sprays or rinses can help with dry mouth.

            • Glycopyrrolate (Robinul) can cause constipation. To help with constipation, drink plenty of water and eat more foods high in fiber, such as fruits and vegetables. Regular exercise can also relieve constipation. Let your provider know if your constipation becomes bothersome, as you might need to use certain OTC medications.

              • If you have diarrhea that doesn't go away while taking glycopyrrolate (Robinul), let your healthcare provider know. This could be a sign of a more serious problem, such as stomach blockage.

                faqs

                Frequently asked questions about Glycopyrrolate (Robinul)

                Why isn't glycopyrrolate (Robinul) commonly used to treat stomach ulcers?
                Glycopyrrolate (Robinul) isn't used as commonly to treat stomach ulcers anymore. A group of medications known as proton-pump inhibitors is often a first-choice option to treat stomach ulcers. Discuss with your healthcare provider to make sure the right medication is prescribed for you.
                Can I take all of my doses of glycopyrrolate (Robinul) at one time?
                No. Glycopyrrolate (Robinul) should be taken two to three times a day. If you're using glycopyrrolate (Robinul) three times a day, take your dose in the morning, early afternoon, and at bedtime. If you're using the 1 mg tablet and having more symptoms at night, your provider might have you take two doses at bedtime. Don't combine or adjust doses without discussing it with your provider first, as this can lead to more side effects.
                Will taking glycopyrrolate (Robinul) make me sleepy?
                Glycopyrrolate (Robinul) can make you sleepy and cause blurred vision. Don't drive or do anything that requires you to be alert until you know how the medication affects you.
                Can I take glycopyrrolate (Robinul) if I'm pregnant?
                There haven't been enough studies looking at how glycopyrrolate (Robinul) affects pregnant or breastfeeding women. If you're pregnant or breastfeeding, discuss the risks and benefits with your healthcare provider before taking glycopyrrolate (Robinul).
                What's the difference between glycopyrrolate (Robinul) and Dartisla ODT (glycopyrrolate)?
                Glycopyrrolate (Robinul) and Dartisla ODT contain glycopyrrolate as their main ingredient, and they are both FDA approved as an add-on treatment for stomach ulcers. But while glycopyrrolate (Robinul) is a tablet that you swallow, Dartisla ODT is an orally disintegrating tablet that dissolves on the top of your tongue. Make sure you know which one you're using because taking it the right way affects how well it works.
                What's the difference between glycopyrrolate (Robinul) and glycopyrrolate (Cuvposa)?
                Glycopyrrolate (Cuvposa) is an oral solution used to reduce severe drooling in children ages 3 to 16 with certain conditions that affect the brain. Glycopyrrolate (Robinul) is a tablet used as an add-on treatment for stomach ulcers, and it can't be used in children under the age of 12. Glycopyrrolate (Robinul) and glycopyrrolate (Cuvposa) can't be substituted for each other because they are available in different dosage forms and contain different amounts of glycopyrrolate.
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                What are the risks and warnings for Glycopyrrolate (Robinul)?

                Glycopyrrolate (Robinul) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                risk-warning

                Worsening glaucoma

                • Risk factors: Glaucoma

                  Glycopyrrolate (Robinul) can cause higher pressure in the eye, especially for people who already have glaucoma, a common eye condition. If you have dilated pupils with eye redness or pain, stop taking the medication and let your healthcare provider know right away.

                  risk-warning

                  Heat stroke or fever

                  • Risk factors: Hot weather | Strenuous exercise | Taking other anticholinergic medications | Older adults

                    Glycopyrrolate (Robinul) causes you to sweat less, which can lead to fever or heat strokes in hot weather. Be careful taking glycopyrrolate (Robinul) when it's hot outside. To help with this, make sure you cool yourself down by resting in the shade, drinking cold water, and taking breaks while exercising.

                    risk-warning

                    Stomach blockage

                    • Risk factors: History of surgical procedures of the intestines, such as ileostomy or colostomy | Older adults

                      Glycopyrrolate (Robinul) can cause stomach blockage. If you have diarrhea after taking glycopyrrolate (Robinul), it could be an early sign of a stomach blockage, especially in people who have had surgical procedures in the intestine. Let your healthcare provider know if you have diarrhea that doesn’t go away because you might need to take a different medication.

                      risk-warning

                      Drowsiness and blurred vision

                      • Risk factors: Taking other medications that make you sleepy or cause blurred vision

                        Glycopyrrolate (Robinul) can cause drowsiness or blurred vision. Don't drive or do any activities that require concentration until you know how glycopyrrolate (Robinul) affects you.

                        risk-warning

                        Worsening of other health conditions

                        Some conditions can worsen if you take glycopyrrolate (Robinul). For example, if you have heart problems, such as congestive heart failure or high blood pressure, you need to be careful when taking the medication because it can further raise your blood pressure and heart rate.

                        If you have an inflamed colon (ulcerative colitis), higher doses of glycopyrrolate (Robinul) can slow your stomach and intestinal muscles, which can lead to life-threatening conditions of the intestine. Talk to your healthcare provider if you’re concerned about certain worsening conditions.

                        dosage

                        Glycopyrrolate (Robinul) dosage forms

                        The average cost for 60 tablets of 1mg of Glycopyrrolate (Robinul) is $17.22 with a free GoodRx coupon. This is 75.3% off the average retail price of $69.73.
                        tablet
                        Tablet
                        DosageQuantityPrice as low asPrice per unit
                        1mg60 tablets$17.22$0.29
                        2mg60 tablets$12.00$0.20

                        Typical dosing for Glycopyrrolate (Robinul)

                        Glycopyrrolate (Robinul) oral tablets:

                        • The typical starting dose is 1 mg by mouth three times daily. The maximum daily dose is 8 mg. Your healthcare provider will work with you to adjust your dose based on your symptoms and side effects.

                        Dartisla ODT (glycopyrrolate) orally disintegrating tablets:

                        • The typical starting dose is 1.7 mg dissolved on the top of your tongue two to three times daily. The maximum daily dose is 6.8 mg. Your healthcare provider will work with you to adjust your dose based on your symptoms and side effects.

                        Glycopyrrolate is also available as an injection into the muscle used for people who can't use oral tablets to treat stomach ulcers. It's also used for people undergoing surgery for anesthesia.

                        interactions

                        Interactions between Glycopyrrolate (Robinul) and other drugs

                        Glycopyrrolate (Robinul) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Glycopyrrolate (Robinul). Please note that only the generic name of each medication is listed below.

                        Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                        • Potassium

                        Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                        drug-cost

                        How much does Glycopyrrolate (Robinul) cost?

                        To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                        Robinul (brand)
                        GoodRx lowest price

                        $12.00

                        (save 98.52%)
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                        contraindications-icon

                        Glycopyrrolate (Robinul) contraindications

                        Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Glycopyrrolate (Robinul) will not be safe for you to take.

                        • Glaucoma

                        • Blocked urine flow

                        • Stomach blockage

                        • Loss of movement in the intestine muscles of older people

                        • Inflammation of the intestines (ulcerative colitis)

                        • Unstable heart during serious blood loss

                        • Abnormal muscle weakness (myasthenia gravis)

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                        Glycopyrrolate (Robinul) images

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                        References

                        Best studies we found

                        Debanto, J. (2021). Peptic ulcer disease. American College of Gastroenterology.

                        Edenbridge Pharmaceuticals LLC. (2021). DARTISLA ODT- glycopyrrolate orally disintegrating tablets tablet, orally disintegrating [package insert]. DailyMed.

                        Fresenius Kabi USA, LLC. (2023). GLYCOPYRROLATE- glycopyrrolate injection [package insert]. DailyMed.

                        View All References (2)

                        Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc. (2022). GLYCOPYRROLATE tablet [package insert]. DailyMed.

                        Quinn Pharmaceuticals. (2022). GLYCOPYRROLATE tablet [package insert]. DailyMed.

                        GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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