Key takeaways
Tenoretic (atenolol/chlorthalidone) and Hyzaar (losartan/hydrochlorothiazide) are both combination medications used to treat high blood pressure, but they work in different ways. Tenoretic combines a beta blocker (atenolol) and a thiazide-like diuretic (chlorthalidone), while Hyzaar combines an angiotensin II receptor blocker (ARB) (losartan) and a thiazide diuretic (hydrochlorothiazide). Tenoretic is not typically recommended for people just starting blood pressure treatment because its fixed doses are hard to adjust, and Hyzaar is also often used for those who have already been on other blood pressure medications. Both medications can cause dizziness and increased urination, but Tenoretic may also cause tiredness and slow heart rate, while Hyzaar can affect electrolyte levels and potentially cause vision problems. Neither medication is safe to use during pregnancy or breastfeeding.
