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Compare Exforge vs. Cozaar

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Exforge (amlodipine/valsartan) and losartan (Cozaar) are both medications used to treat high blood pressure, but they have some key differences. Exforge is a combination of two medications: amlodipine, a calcium channel blocker (CCB), and valsartan, an angiotensin II receptor blocker (ARB). Losartan, on the other hand, is a single medication that belongs to the ARB class. Both medications are taken once daily and come in lower-cost generic forms. Exforge can cause swelling in the arms and legs due to amlodipine, whereas losartan may cause upper respiratory infections and dizziness. Additionally, losartan is known to protect against stroke and slow down kidney problems in people with Type 2 diabetes. Both medications are not safe to use during pregnancy and can cause high potassium levels.

  • Exforge (amlodipine / valsartan)
    Losartan (Cozaar)
  • Exforge (amlodipine / valsartan)
    Losartan (Cozaar)

  • Summary of Exforge vs. Cozaar

    Summary for CCB / ARB
    Prescription only

    Exforge is a combination blood pressure medication for adults. It contains amlodipine (a calcium channel blocker, or CCB) and valsartan (an angiotensin receptor blocker, or ARB). It comes as a tablet that's taken by mouth, typically once per day. Some side effects of Exforge (amlodipine / valsartan) include swelling throughout the body and dizziness. This medication is available as generics.

    Summary for ARB
    Prescription only

    Losartan, also known by the brand name Cozaar, is a first-choice medication that's used to lower blood pressure. It's also shown to protect against stroke in certain people. In addition, this medication can slow down the worsening of kidney problems in certain people with diabetes. Losartan (Cozaar) belongs to the drug class called angiotensin II receptor blockers (ARBs). This medication is taken by mouth once daily and is available as a lower-cost generic. Side effects can include dizziness, fatigue, and upper respiratory infections.

  • Indications of Exforge vs. Cozaar

    Indications for
    •High blood pressure in adults
    Indications for
    •High blood pressure
    •Lower the risk of stroke in people with high blood pressure who have a thickened heart (left ventricular hypertrophy)
    •Slow down the worsening of kidney problems in people with Type 2 diabetes and high blood pressure

  • Pros and Cons of Exforge vs. Cozaar

    Pros and Const for CCB / ARB
    Pros
    •Convenient to take a combination of two medications in one pill
    •Only taken once a day
    •Available as a lower-cost generic
    Cons
    •Not safe to take while pregnant or breastfeeding
    •Might not be a good choice for people with liver problems
    •Can cause swelling in the arms and legs
    Pros and Const for ARB
    Pros
    •A first-choice blood pressure medication, including for those with heart failure, diabetes, and kidney problems
    •Taken once per day
    •Can be taken by children as young as 6 years old
    •Works similarly to angiotensin-converting enzyme (ACE) inhibitors, but with fewer side effects, like cough and swelling
    Cons
    •Might cause dizziness
    •Might not work as well for Black people as other blood pressure medications do
    •Not safe to use during pregnancy
    •Can interact with medications like lithium and nonsteroidal anti-inflammatory drugs (NSAIDs)

  • Common Side Effects of Exforge vs. Cozaar

    Common Side Effects for
    •Swelling in legs or arms (5%)
    •Sore throat, runny nose, and other cold-like symptoms (3-4%)
    •Dizziness (2%)
    Common Side Effects for
    •Upper respiratory infection (e.g., common cold; 8%)
    •Dizziness (3%)
    •Stuffy nose (2%)
    •Back pain (2%)

  • Warnings of Exforge vs. Cozaar

    Common Side Effects for
    •Harm to unborn baby
    •Low blood pressure
    •Risk of heart attack or chest pain
    •Possible kidney damage in certain people
    •High potassium levels
    Common Side Effects for
    •Harm to unborn baby
    •Low blood pressure
    •Kidney damage
    •High potassium levels

  • Prices with our coupons for Exforge vs. Cozaar

    Learn more about Exforge
    Learn more about Losartan

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