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Hyzaar vs. Coreg

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Hyzaar (losartan/hydrochlorothiazide) and carvedilol (Coreg) are both used to treat high blood pressure, but they belong to different medication classes and have different uses. Hyzaar is a combination of an angiotensin II receptor blocker (ARB) and a diuretic, taken once daily, and is also used to lower the risk of stroke in people with high blood pressure and an enlarged left ventricle. Carvedilol, a beta blocker, is taken either twice daily in its immediate-release form or once daily in its extended-release form, and is also used to manage heart failure and reduce the risk of death after a heart attack. While Hyzaar can cause increased urination and should be avoided during pregnancy, carvedilol can cause tiredness, dry eyes, and should not be taken if you have asthma or severe liver problems. Additionally, both medicatiosn are available as lower-cost generics.

Hyzaar

(losartan / hydrochlorothiazide)

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Carvedilol

(Coreg)

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Summary for Hyzaar

Prescription only

Hyzaar (losartan / hydrochlorothiazide) is a combination medication that contains two first-choice options for lowering blood pressure. This medication is taken by mouth once daily. Like other blood pressure medications, Hyzaar (losartan / hydrochlorothiazide) can cause you to feel dizzy, especially when you first start this medication or when your provider raises your dose.

Indications for Hyzaar

Pros and Cons for Hyzaar

Pros

  • Contains two first-choice blood pressure medications
  • Convenient to take a combination of two medications in one pill taken just once a day
  • Protects your kidneys, which is especially useful for people with diabetes or mild-to-moderate kidney disease
  • Taken by mouth once per day

Cons

  • Can make you urinate more often
  • Must be avoided in pregnant females
  • More difficult to customize the dose since Hyzaar (losartan / hydrochlorothiazide) is a combination of two medications
  • Only available as a tablet

Common Side Effects for Hyzaar

  • Upper respiratory tract infection (i.e., common cold; 6%)
  • Dizziness (6%)
  • Back pain (2%)

Warnings for Hyzaar

  • Not for use during pregnancy
  • Low blood pressure
  • Kidney damage
  • Changes in electrolyte, blood sugar, and cholesterol levels
  • Vision problems
  • Lupus

Summary for Coreg

Prescription only

Carvedilol (Coreg) is used to treat high blood pressure, manage heart failure, and help with heart problems after a heart attack. It belongs to the beta blocker drug class. This medication comes as a tablet that's taken by mouth twice daily, and as an oral extended-release (ER) capsule (brand name Coreg CR) that's taken once daily. Common side effects include dizziness, feeling tired, and diarrhea.

Indications for Coreg

  • High blood pressure
  • Heart failure
  • Lower the risk of death from heart-related problems after a heart attack

Pros and Cons for Coreg

Pros

  • Taken by mouth
  • Comes as a once-daily extended-release formulation
  • Dose can be adjusted based on your response
  • Available as a lower-cost generic

Cons

  • Need to take with food
  • Can cause you to feel more tired
  • Can cause dry eyes if you wear contact lenses
  • Shouldn't be taken if you have asthma or an asthma-related condition

Common Side Effects for Coreg

  • Dizziness (6%)

Please note: These side effects were reported by people who took carvedilol (Coreg) in clinical studies for high blood pressure.

Warnings for Coreg

  • Worsening chest pain and heart attacks
  • Slow heart rate and low blood pressure
  • Heart failure
  • Hiding symptoms of low blood sugar
  • Risk of difficulty breathing
  • Hiding symptoms of high thyroid hormone
  • Risk of kidney problems
  • Severe allergic reactions
  • Greater risk during surgery
  • Risk of eye problems during surgery

Prices with our coupons for Hyzaar vs. Coreg

Price Card Drug Icon
Losartan/HCTZ30 tablets / 100mg/25mg
$12.59$20.73
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Carvedilol180 tablets / 25mg
$20.25$223.12
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