Key takeaways
Exforge (amlodipine/valsartan) and lisinopril (Zestril) are both medications used to lower blood pressure, but they work in different ways. Exforge is a combination of two medications: amlodipine, a calcium channel blocker (CCB), and valsartan, an angiotensin II receptor blocker (ARB). It is typically taken once a day and is available as a generic. Common side effects include swelling in the legs and dizziness. Lisinopril, on the other hand, is an angiotensin-converting enzyme (ACE) inhibitor that also treats heart failure and reduces the risk of death after a heart attack. It can cause a dry cough, dizziness, and headache, and is also available as a generic. Unlike Exforge, lisinopril can be taken by children as young as six years old. Both medications should not be used during pregnancy.
