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Compare Zestoretic vs. Diovan HCT

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Zestoretic (lisinopril / hydrochlorothiazide)
    Diovan hct (valsartan / hydrochlorothiazide)
  • Zestoretic (lisinopril / hydrochlorothiazide)
    Diovan hct (valsartan / hydrochlorothiazide)

  • Summary of Zestoretic vs. Diovan HCT

    Summary for ACE inhibitor/Diuretic (water pill) combo
    Prescription only

    Zestoretic is a combination blood pressure medication for adults. It contains lisinopril (an angiotensin-converting enzyme (ACE) inhibitor) and hydrochlorothiazide (a thiazide diuretic). It comes as a tablet that's taken by mouth once per day. Your prescriber will determine your dosage based on how high your blood pressure is and if you're taking other blood pressure medications. Some of the more common side effects it can cause include dizziness, headache, and cough. Zestoretic (lisinopril / hydrochlorothiazide) is available as a generic.

    Summary for ARB / Diuretic (water pill)
    Prescription only

    Diovan HCT (valsartan / hydrochlorothiazide) is a combination of two blood pressure medications. It's typically used when one medication alone doesn't lower your blood pressure enough. Diovan HCT (valsartan / hydrochlorothiazide) is taken by mouth, usually once daily. Keep in mind that it can take 1 to 2 weeks before you start to notice the effects of this medication on you blood pressure. The most common side effect of Diovan HCT (valsartan / hydrochlorothiazide) is dizziness, especially when you first start taking this medication or when your provider adjusts your dose.

  • Indications of Zestoretic vs. Diovan HCT

    Indications for
    •High blood pressure in adults
    Indications for
    •High blood pressure

  • Pros and Cons of Zestoretic vs. Diovan HCT

    Pros and Const for ACE inhibitor/Diuretic (water pill) combo
    Pros
    •Combines two medications in one pill
    •Taken by mouth
    •Taken once daily
    Cons
    •Can make you urinate more often
    •Might not be appropriate for someone with a sulfa allergy
    •Shouldn't take during pregnancy or breastfeeding
    Pros and Const for ARB / Diuretic (water pill)
    Pros
    •Contains two first-choice medications to lower blood pressure
    •Conveniently combines two medications into one tablet
    •Only taken once a day
    •Available as a lower-cost generic
    Cons
    •Comes in fixed dosage strengths, so it might be harder for your provider to adjust the doses of the individual medications
    •Might require regular blood tests to see how it's affecting your electrolytes and kidneys
    •Not safe to use if you're pregnant or breastfeeding
    •Makes you urinate more

  • Common Side Effects of Zestoretic vs. Diovan HCT

    Common Side Effects for
    •Dizziness (8%)
    •Headache (5%)
    •Cough (4%)
    •Extreme tiredness (4%)
    •Feeling lightheaded when standing after sitting or lying down (3%)
    Common Side Effects for
    •Dizziness (6%)
    •Common cold (2%)
    •Feeling lightheaded when standing up from a seated or lying down position (1%)

  • Warnings of Zestoretic vs. Diovan HCT

    Common Side Effects for
    •Not for use during pregnancy
    •Angioedema (swelling)
    •Low blood pressure
    •Kidney damage
    •Changes in electrolyte, blood sugar, and cholesterol levels
    •Vision problems
    •Lupus
    Common Side Effects for
    •Not for use during pregnancy
    •Low blood pressure
    •Worsening kidney problems
    •Severe allergic reaction
    •Changes in electrolytes
    •Vision problems
    •Lupus
    •Interactions with other medications

  • Prices with our coupons for Zestoretic vs. Diovan HCT

    Learn more about Zestoretic
    Learn more about Diovan hct

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