Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Lisinopril (Zestril) and ramipril (Altace) are both angiotensin-converting enzyme (ACE) inhibitors used to treat high blood pressure and heart failure. Lisinopril is available in both tablet and liquid forms, making it easier for people who have trouble swallowing pills. Ramipril is only available as a capsule that can be opened and sprinkled on food. Lisinopril is typically taken once daily, whereas Ramipril might need to be taken once or twice daily depending on the dose. Lisinopril can be prescribed to children aged 6 and older for high blood pressure, but Ramipril is only for adults. Both medications can cause a dry cough, which is a common side effect of ACE inhibitors. Neither medication should be used during pregnancy due to the risk of harm to the unborn baby. Both Lisinopril and Ramipril are available as lower-cost generics.
Lisinopril (Zestril)
Ramipril
Lisinopril (Zestril)
Ramipril
Summary of Lisinopril vs. Altace
Summary for ACE inhibitor
Prescription only
Lisinopril (Zestril) is an angiotensin-converting enzyme (ACE) inhibitor that's a first-choice medication used for lowering blood pressure. It's also approved to treat symptoms of heart failure and also to lower the risk of death after a heart attack. Lisinopril (Zestril) is a tablet that's taken by mouth, typically once daily. It's also available as an oral solution. Some common side effects of this medication include cough, dizziness, and headache.
Summary for ACE inhibitor
Prescription only
Ramipril is an angiotensin-converting enzyme (ACE) inhibitors. This medication treats high blood pressure by relaxing blood vessels. It can also ease heart failure symptoms after a heart attack. Ramipril is taken by mouth, typically once or twice daily, by adults. Some of the more common side effects of this medication include headache, dizziness, and feeling tired. Ramipril is generic only because the brand name Altace is no longer available.