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Lisinopril vs. Prazosin

Lisinopril (Zestril) is an angiotensin-converting enzyme inhibitor, or ACE inhibitor. It's used to treat high blood pressure in people 6 years and older. In adults, it's also approved to manage heart failure and to lower the risk of death after a heart attack. Lisinopril (Zestril) comes as a tablet that's taken by mouth once daily. There's also an oral solution available under the brand name Qbrelis. Some side effects include dizziness, cough, and headache.

• High blood pressure in people ages 6 years and older
• Heart failure in adults
• Lowering the risk of death after a heart attack in adults

• Dizziness (up to 19%)
• Low blood pressure (up to 11%)
• Higher creatinine levels (up to 10%)

• Harm to an unborn baby
• Angioedema (swelling)
• Low blood pressure
• Possible worsening of kidney problems
• High potassium levels
• Liver problems

Prazosin (Minipress) is an alpha blocker that's used to lower high blood pressure. It works by relaxing your blood vessels, so blood flows through more easily. Prazosin (Minipress) is taken by mouth, typically 2 to 3 times a day. But it isn't a first-choice medication to lower blood pressure because it can cause bothersome side effects like dizziness, headache, and sleepiness.

• High blood pressure (hypertension)

• Dizziness (10%)
• Headache (8%)
• Drowsiness (8%)
• Lack of energy (7%)
• Weakness (7%)
• Pounding heart (5%)
• Nausea (5%)

• Dangerously low blood pressure and risk of fainting
• Painful erection (priapism)
• Eye problems during surgery