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Compare Lisinopril vs. Coreg

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lisinopril (Zestril) and carvedilol (Coreg) are both used to treat high blood pressure and heart-related issues, but they belong to different medication classes and work in different ways. Lisinopril is an ACE inhibitor that relaxes blood vessels by blocking a protein called ACE, while carvedilol is a beta blocker that lowers blood pressure by relaxing blood vessels and slowing down the heart rate. Lisinopril is typically taken once daily and is available as both a tablet and a liquid, making it a good option for people who have trouble swallowing pills. In contrast, carvedilol comes in immediate-release tablets taken twice daily and extended-release capsules taken once daily. Common side effects of Lisinopril include dizziness and headache, whereas carvedilol can cause dizziness, tiredness, and diarrhea. Additionally, lisinopril is more likely to cause a dry cough and should not be used during pregnancy, while carvedilol should be taken with food and is not recommended for people with asthma. Both medications are available in lower-cost generic forms.

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  • Lisinopril (Zestril)
    Carvedilol (Coreg)
  • Lisinopril (Zestril)
    Carvedilol (Coreg)

  • Summary of Lisinopril vs. Coreg

    Summary for ACE inhibitor
    Prescription only

    Lisinopril (Zestril) is an angiotensin-converting enzyme (ACE) inhibitor that's a first-choice medication used for lowering blood pressure. It's also approved to treat symptoms of heart failure and also to lower the risk of death after a heart attack. Lisinopril (Zestril) is a tablet that's taken by mouth, typically once daily. It's also available as an oral solution. Some common side effects of this medication include cough, dizziness, and headache.

    Summary for Beta blocker
    Prescription only

    Carvedilol (Coreg) is used to treat high blood pressure, manage heart failure, and help with heart problems after a heart attack. It belongs to the beta blocker drug class. This medication comes as a tablet that's taken by mouth twice daily, and as an oral extended-release (ER) capsule (brand name Coreg CR) that's taken once daily. Common side effects include dizziness, feeling tired, and diarrhea.

  • Indications of Lisinopril vs. Coreg

    Indications for
    •High blood pressure
    •Heart failure
    •Lower the risk for death after a heart attack
    Indications for
    •High blood pressure
    •Heart failure
    •Lower the risk of death from heart-related problems after a heart attack

  • Pros and Cons of Lisinopril vs. Coreg

    Pros and Const for ACE inhibitor
    Pros
    •A first-choice blood pressure medication
    •Taken by mouth once per day
    •Can be taken by children as young as 6 years old for treatment of high blood pressure
    •Available as a liquid (Qbrelis), good option for people who've difficulty swallowing tablets
    Cons
    •More likely to cause a dry cough, compared to ARBs
    •Can't be taken during pregnancy or breastfeeding
    •Might not work as well for lowering high blood pressure in black people
    Pros and Const for Beta blocker
    Pros
    •Taken by mouth
    •Comes as a once-daily extended-release formulation
    •Dose can be adjusted based on your response
    •Available as a lower-cost generic
    Cons
    •Need to take with food
    •Can cause you to feel more tired
    •Can cause dry eyes if you wear contact lenses
    •Shouldn't be taken if you have asthma or an asthma-related condition

  • Common Side Effects of Lisinopril vs. Coreg

    Common Side Effects for
    •Dizziness (up to 19%)
    •Low blood pressure (7-11%)
    •Higher creatinine levels (7-10%)
    •Headache (6%)
    Common Side Effects for
    •Dizziness (6%)

    Please note: These side effects were reported by people who took carvedilol (Coreg) in clinical studies for high blood pressure.

  • Warnings of Lisinopril vs. Coreg

    Common Side Effects for
    •Not for use during pregnancy
    •Angioedema (swelling)
    •Low blood pressure
    •Worsening kidney problems
    •Heart problems due to high potassium
    •Liver problems
    Common Side Effects for
    •Worsening chest pain and heart attacks
    •Slow heart rate and low blood pressure
    •Heart failure
    •Hiding symptoms of low blood sugar
    •Risk of difficulty breathing
    •Hiding symptoms of high thyroid hormone
    •Risk of kidney problems
    •Severe allergic reactions
    •Greater risk during surgery
    •Risk of eye problems during surgery

  • Prices with our coupons for Lisinopril vs. Coreg

    Learn more about Lisinopril
    Learn more about Carvedilol

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