Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Exforge vs. Twynsta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Exforge (amlodipine/valsartan) and telmisartan/amlodipine (Twynsta) are both combination medications used to treat high blood pressure in adults, but they have some differences. Exforge combines amlodipine, a calcium channel blocker (CCB), with valsartan, an angiotensin II receptor blocker (ARB). On the other hand, telmisartan/amlodipine combines amlodipine with telmisartan, another ARB. Both medications are taken once daily and are available as generics, making them more affordable. However, the brand name for telmisartan/amlodipine, Twynsta, has been discontinued. Common side effects for both include swelling and dizziness, but telmisartan/amlodipine can also cause back pain. Neither medication is safe to use during pregnancy or breastfeeding. Both medications are effective and provide the convienence of combining two medications into one pill.

  • Exforge (amlodipine / valsartan)
    Telmisartan / amlodipine
  • Exforge (amlodipine / valsartan)
    Telmisartan / amlodipine

  • Summary of Exforge vs. Twynsta

    Summary for CCB / ARB
    Prescription only

    Exforge is a combination blood pressure medication for adults. It contains amlodipine (a calcium channel blocker, or CCB) and valsartan (an angiotensin receptor blocker, or ARB). It comes as a tablet that's taken by mouth, typically once per day. Some side effects of Exforge (amlodipine / valsartan) include swelling throughout the body and dizziness. This medication is available as generics.

    Summary for ARB / CCB
    Prescription only

    Telmisartan / amlodipine is a combination medication containing an angiotensin II receptor blocker (telmisartan) and a calcium channel blocker (amlodipine). It's used to treat adults with high blood pressure. The typical dosage is to take one tablet by mouth once a day. Common side effects include swelling and dizziness. Although the brand Twynsta has been discontinued, the generic medication is still available.

  • Indications of Exforge vs. Twynsta

    Indications for
    •High blood pressure in adults
    Indications for
    •High blood pressure

  • Pros and Cons of Exforge vs. Twynsta

    Pros and Const for CCB / ARB
    Pros
    •Convenient to take a combination of two medications in one pill
    •Only taken once a day
    •Available as a lower-cost generic
    Cons
    •Not safe to take while pregnant or breastfeeding
    •Might not be a good choice for people with liver problems
    •Can cause swelling in the arms and legs
    Pros and Const for ARB / CCB
    Pros
    •Contains two first-choice medications for treating high blood pressure
    •Convenient to take a single pill that's a combination of two medications
    •Taken once a day by mouth with or without food
    •Available as a lower-cost generic
    Cons
    •Can cause swelling in the arms and legs
    •More difficult to adjust the amount of each individual ingredient in the medication
    •Can interact with other medications
    •Not safe in pregnancy or breastfeeding

  • Common Side Effects of Exforge vs. Twynsta

    Common Side Effects for
    •Swelling in legs or arms (5%)
    •Sore throat, runny nose, and other cold-like symptoms (3-4%)
    •Dizziness (2%)
    Common Side Effects for
    •Swelling (5%)
    •Dizziness (3%)
    •Back pain (2%)

  • Warnings of Exforge vs. Twynsta

    Common Side Effects for
    •Harm to unborn baby
    •Low blood pressure
    •Risk of heart attack or chest pain
    •Possible kidney damage in certain people
    •High potassium levels
    Common Side Effects for
    •Harm to unborn baby
    •Low blood pressure
    •High potassium levels
    •Risk of heart attack or chest pain
    •Possible kidney damage in certain people

  • Prices with our coupons for Exforge vs. Twynsta

    Learn more about Exforge
    Learn more about Telmisartan / amlodipine

Compare other Hypertension drugs

Exforge vs AtacandExforge vs AzorExforge vs CozaarExforge vs DiovanExforge vs MicardisExforge vs NorvascExforge vs PrinivilExforge vs QbrelisExforge vs TenoreticExforge vs TwynstaExforge vs ZestoreticExforge vs ZestrilHyzaar vs ExforgeLopressor Hct vs ExforgeZiac vs ExforgeAtacand vs DiovanAtacand vs PrinivilAvapro vs DiovanCapoten vs DiovanCapoten vs PrinivilCozaar vs DiovanEnalapril vs DiovanFelodipine vs DiovanLisinopril vs DiovanMicardis vs DiovanMicardis vs PrinivilNifedipine vs DiovanNorvasc vs PrinivilPrinivil vs PrinzideZestoretic vs Diovan
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.