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Compare Ziac vs. Dutoprol

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ziac (bisoprolol/hydrochlorothiazide) and Dutoprol (metoprolol succinate/hydrochlorothiazide) are combination medications used to treat high blood pressure. They each contain a beta blocker and a diuretic, which work together to lower blood pressure. However, there are several differences between them. Ziac combines bisoprolol, a beta blocker, with hydrochlorothiazide, a diuretic, and is available as a prescription medication taken once daily. Dutoprol, on the other hand, combined metoprolol succinate, another beta blocker, with hydrochlorothiazide, but has been discontinued and is no longer available. Both medications share common side effects like dizziness and tiredness. Ziac comes in fixed dosage strengths, which can make it harder to adjust the dosages of the individual ingredients. While Dutoprol is not available, the medications it contained can be prescribed separately.

  • Ziac (bisoprolol / hydrochlorothiazide)
    Dutoprol (metoprolol succinate / hydrochlorothiazide)
  • Ziac (bisoprolol / hydrochlorothiazide)
    Dutoprol (metoprolol succinate / hydrochlorothiazide)

  • Summary of Ziac vs. Dutoprol

    Summary for Beta blocker / Diuretic (water pill)
    Prescription only

    Ziac, the brand name for bisoprolol/hydrochlorothiazide or bisoprolol/HCTZ, is a combination medication. It's used to treat high blood pressure in adults. It contains two classes of medications: a beta blocker (bisoprolol) and a diuretic (hydrochlorothiazide). It comes as a tablet that's taken by mouth once a day. Some side effects include dizziness and tiredness.

    Summary for Beta blocker / HCTZ

    Dutoprol (metoprolol succinate / hydrochlorothiazide) is a combination medication used to control blood pressure to lower the risk of a heart attack or stroke. This medication has been discontinued by the manufacturer and is no longer available in the United States.

  • Indications of Ziac vs. Dutoprol

    Indications for
    •High blood pressure
    Indications for
    •High blood pressure

  • Pros and Cons of Ziac vs. Dutoprol

    Pros and Const for Beta blocker / Diuretic (water pill)
    Pros
    •Only taken once daily
    •Combines two blood pressure medications into one tablet
    •Can take with or without food
    Cons
    •Comes in fixed dosage strengths, so it's harder to adjust the doses of the individual ingredients
    •Can make you urinate more often
    •Not a good option for people with a sulfa allergy
    Pros and Const for Beta blocker / HCTZ
    Pros
    Cons

  • Common Side Effects of Ziac vs. Dutoprol

    Common Side Effects for
    •Dizziness (5%)
    •Tiredness (5%)
    •Headache (5%)
    •Diarrhea (4%)
    Common Side Effects for

  • Warnings of Ziac vs. Dutoprol

    Common Side Effects for
    •Risk of heart problems after stopping Ziac (bisoprolol / hydrochlorothiazide) suddenly
    •Risk of heart failure
    •Changes in fluids and electrolytes in the body
    •Hidden symptoms of low blood sugar
    •Hidden symptoms of overactive thyroid
    •Caution use in people with breathing problems
    •Caution use in people with peripheral artery disease (PAD)
    •Risk of vision problems and glaucoma
    Common Side Effects for

  • Prices with our coupons for Ziac vs. Dutoprol

    Learn more about Ziac
    Learn more about Dutoprol

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