Key takeaways
Metoprolol tartrate (Lopressor) and prazosin (Minipress) are both used to manage high blood pressure, but they belong to different medication classes and have distinct uses and side effects. Metoprolol is a beta blocker that also treats chest pain and lowers the risk of death after a heart attack. It works by slowing down the heart, which reduces pressure on blood vessels and the heart's oxygen demand. Prazosin, on the other hand, is an alpha blocker that relaxes blood vessels to improve blood flow. While metoprolol is typically taken twice daily with food, prazosin is taken 2 to 3 times a day and can be taken with or without food. Common side effects of metoprolol include tiredness and dizziness, whereas prazosin often causes dizziness, headache, and drowsiness. Additionally, prazosin is sometimes used off-label for PTSD-related nightmares, though its effectiveness for this use is debated. Both medications are available in generic forms, making them more affordable options.
