Lopressor vs. Dutoprol for Hypertension: Important Differences and Potential Risks.

Key takeaways

Metoprolol tartrate (Lopressor) and metoprolol succinate/hydrochlorothiazide (Dutoprol) are both used to treat high blood pressure. Metoprolol tartrate is a beta blocker, while Dutoprol is a combination of a long-acting beta blocker (metoprolol succinate) and a diuretic (hydrochlorothiazide). Metoprolol tartrate is also FDA-approved for treating chest pain and reducing the risk of death after a heart attack. Dutoprol has been discontinued, but its ingredients are still available individually. Metoprolol tartrate is typically taken twice daily and is available as a lower-cost generic, while Dutoprol was taken once daily. Common side effects of metoprolol tartrate include dizziness and tiredness. Metoprolol tartrate can interact with medications that affect heart rate and blood pressure.

Metoprolol tartrate

(Lopressor)

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Dutoprol

(metoprolol succinate / hydrochlorothiazide)

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Summary for Lopressor

Prescription only

Metoprolol tartrate (Lopressor) is a beta blocker used to treat chest pain and high blood pressure in adults. It can also lower the risk of death after a heart attack. You take it by mouth, typically once or twice a day, but your dose depends on your condition. Side effects include dizziness, shortness of breath, and it can make you tired.

Indications for Lopressor

High blood pressure
Chest pain (angina)
Lower risk of death after a heart attack

Pros and Cons for Lopressor

Pros

Fast-acting — works quickly after you take it
First choice treatment after a heart attack
Available in different strengths, so your dose can be adjusted easily
Possible option for those who are breastfeeding

Cons

Need to take with food
Typically need to take more than once a day
Not a first-choice treatment for high blood pressure, unless you have certain heart conditions
Can hide symptoms of low blood sugar

Common Side Effects for Lopressor

Tiredness (10%)
Dizziness (10%)
Diarrhea (5%)
Rash (5%)
Depression (5%)

Warnings for Lopressor

Risks of stopping treatment suddenly
Worsening heart failure
Risk of difficulty breathing
Major surgery
Hiding symptoms of low blood sugar
Hiding symptoms of overactive thyroid
Severe allergic reactions

Summary for Dutoprol

Discontinued

Dutoprol (metoprolol succinate / hydrochlorothiazide) is a combination medication used to control blood pressure to lower the risk of a heart attack or stroke. This medication has been discontinued by the manufacturer and is no longer available in the United States.