Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Captopril (Capoten) and Valsartan (Diovan) are both medications used to treat high blood pressure and heart failure. But they have some important differences. Captopril is an angiotensin-converting enzyme (ACE) inhibitor, while Valsartan is an angiotensin II receptor blocker (ARB). Captopril is also used to prevent kidney problems in people with diabetes, which is not an approved use for Valsartan. Captopril is taken two to three times a day on an empty stomach, whereas Valsartan is usually taken once or twice a day and can be taken with or without food. Both medications are available as generics, but Captopril is only available in tablet form, while Valsartan comes in both tablet and liquid forms. Common side effects of captopril include a dry cough and changes in taste, while valsartan may cause dizziness and fatigue. Both medications can raise potassium levels, but valsartan is less likely to cause a cough compared to captopril. Additionally, both medications are not recommended during pregnancy.
Captopril
Valsartan (Diovan)
Captopril
Valsartan (Diovan)
Summary of Capoten vs. Diovan
Summary for ACE inhibitor
Prescription only
Captopril is an angiotensin-converting enzyme (ACE) inhibitor. It's used in adults to treat high blood pressure, heart failure, and to prevent the worsening of kidney problems in people who have diabetes. Captopril is available as a tablet that's taken by mouth two to three times per day. Your healthcare team will help determine your dose based on different factors, such as how high your blood pressure is and what other medications you're taking. Side effects include a dry cough, changes in taste, and dizziness. Brand name Capoten has been discontinued; captopril is only available as a generic medication.
Summary for ARB
Prescription only
Valsartan, also known by its brand name, Diovan, is an angiotensin II receptor blocker (ARB). It's used to treat high blood pressure in adults and children. It's also used to lower the risk of serious heart-related problems in adults with heart failure or in adults after a heart attack. Valsartan (Diovan) is available as a lower-cost generic and comes as a tablet and liquid. The dosage depends on your condition, but it's typically taken by mouth once or twice per day. Potential side effects of valsartan (Diovan) include dizziness and fatigue.