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Compare Capoten vs. Aceon

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Captopril (Capoten) and perindopril (Aceon) are both ACE inhibitor medications used to treat high blood pressure and certain heart-related conditions, including lowering the risk of heart attack. Captopril is taken two to three times a day on an empty stomach, while perindopril is usually taken once a day. Both medications are available as a lower-cost generic. Side effects of both medications include a dry cough and dizziness, and both may rarely cause angioedema. Both medications can interact with NSAIDs like ibuprofen (Motrin) and naproxen (Aleve) and are not recommended during pregnancy.

  • Captopril
    Perindopril
  • Captopril
    Perindopril

  • Summary of Capoten vs. Aceon

    Summary for ACE inhibitor
    Prescription only

    Captopril is an angiotensin-converting enzyme (ACE) inhibitor. It's used in adults to treat high blood pressure, heart failure, and to prevent the worsening of kidney problems in people who have diabetes. Captopril is available as a tablet that's taken by mouth two to three times per day. Your healthcare team will help determine your dose based on different factors, such as how high your blood pressure is and what other medications you're taking. Side effects include a dry cough, changes in taste, and dizziness. Brand name Capoten has been discontinued; captopril is only available as a generic medication.

    Summary for ACE inhibitor
    Prescription only

    Perindopril is a prescription medication that's used to treat high blood pressure. It's also used to lower the risk of death or heart attack in certain people with coronary artery disease (CAD). The dosage for perindopril can differ if you're older, have kidney problems, or are taking diuretics ("water pills"). Common side effects include dry cough, dizziness, and back pain. Although the brand name for this medication, Aceon, is discontinued, perindopril is available as a lower-cost, generic tablet.

  • Indications of Capoten vs. Aceon

    Indications for
    •High blood pressure
    •Heart failure (in combination with other medications)
    •Improve survival after heart attack in people who have heart failure
    •Prevent worsening kidney problems in people who have diabetes (diabetic nephropathy)
    Indications for
    •Treatment of high blood pressure
    •Treatment of stable coronary artery disease (CAD) in certain people to lower the risk of death or heart attack

  • Pros and Cons of Capoten vs. Aceon

    Pros and Const for ACE inhibitor
    Pros
    •A first-choice medication for lowering blood pressure for many people
    •Taken by mouth
    •Available as a lower-cost generic
    Cons
    •Taken two to three times per day
    •Need to take on an empty stomach, 1 hour before meals
    •Can't take during pregnancy
    Pros and Const for ACE inhibitor
    Pros
    •Available as a lower-cost generic medication
    •Typically taken once a day
    •Lowers the risk of heart attack or death due to heart problems in people with CAD
    Cons
    •Can’t take while pregnant
    •More likely to cause dry cough compared to angiotensin II receptor blockers (ARBs)
    •Might cause severe swelling of the face, tongue, throat (angioedema)

  • Common Side Effects of Capoten vs. Aceon

    Common Side Effects for
    •Skin rash (up to 7%)
    •Changes in taste (up to 4%)
    •Dry cough (up to 2%)
    •Itching (2%)
    Common Side Effects for
    •Cough (12%)
    •Dizziness (8%)
    •Back pain (6%)

  • Warnings of Capoten vs. Aceon

    Common Side Effects for
    •Not safe during pregnancy
    •Angioedema (swelling) and serious allergic reactions
    •Risk of infection (lower white blood cell count)
    •Low blood pressure
    •Worsening kidney problems
    •High potassium levels
    •Risk of liver problems
    Common Side Effects for
    •Harm to unborn baby
    •Angioedema (swelling)
    •Low blood pressure
    •Worsening kidney problems
    •Low blood cell count
    •High levels of potassium
    •Dry cough
    •Liver problems

  • Prices with our coupons for Capoten vs. Aceon

    Learn more about Captopril
    Learn more about Perindopril

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