Key takeaways
Candesartan (Atacand) and lisinopril (Zestril) are both medications used to treat high blood pressure and heart failure, but they belong to different classes. Candesartan is an angiotensin II receptor blocker (ARB), while lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. Candesartan works by blocking the effects of angiotensin II, a hormone that raises blood pressure, whereas lisinopril blocks a protein that tightens blood vessels. One key difference is that lisinopril is more likely to cause a dry cough, a common side effect of ACE inhibitors. Both medications are taken orally, but lisinopril is available as both a tablet and a liquid, making it a good option for people who have trouble swallowing pills. Additionally, both medications should be avoided during pregnancy due to potential harm to the unborn baby and are available in lower-cost generic forms.
