Key takeaways
Irbesartan (Avapro) and azilsartan (Edarbi) are both angiotensin II receptor blockers (ARBs) used to treat high blood pressure. Irbesartan is also used to treat diabetic kidney disease, while azilsartan is only approved for high blood pressure in adults. Irbesartan is available in both brand name and generic forms, making it a more cost-effective option, whereas azilsartan is only available as a brand-name medication. The typical dose for irbesartan is 150 mg to 300 mg once daily, while azilsartan is usually taken at 40 mg to 80 mg once daily. Common side effects of irbesartan include dizziness and tiredness, while azilsartan may cause diarrhea, nausea, and fatigue. Both medications can cause serious side effects like high potassium levels and kidney problems, and neither is safe to use during pregnancy.
