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Compare Coreg vs. Trandate

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Carvedilol (Coreg) and labetalol (formerly branded as Trandate) are both beta blockers used to lower blood pressure, but they have some differences. Carvedilol is also used to manage heart failure and reduce the risk of death after a heart attack, while labetalol is primarily used for high blood pressure. Carvedilol comes in both immediate-release tablets and extended-release capsules, whereas labetalol is only available in immediate-release form. You need to take carvedilol with food, but labetalol can be taken with or without food as long as you are consistent. Carvedilol can cause weight gain and dry eyes, while labetalol can cause a false-positive urine test for amphetamines. Both medications can make you dizzy and hide symptoms of low blood sugar, but labetalol is noted for causing less of a drop in heart rate compared to other beta blockers.

  • Carvedilol (Coreg)
    Labetalol
  • Carvedilol (Coreg)
    Labetalol

  • Summary of Coreg vs. Trandate

    Summary for Beta blocker
    Prescription only

    Carvedilol (Coreg) is used to treat high blood pressure, manage heart failure, and help with heart problems after a heart attack. It belongs to the beta blocker drug class. This medication comes as a tablet that's taken by mouth twice daily, and as an oral extended-release (ER) capsule (brand name Coreg CR) that's taken once daily. Common side effects include dizziness, feeling tired, and diarrhea.

    Summary for Beta blocker
    Prescription only

    Labetalol is a medication that works as both an alpha blocker and beta blocker. It's used to treat high blood pressure in adults. But it's not a first-choice medication for blood pressure, except during pregnancy. Labetalol is typically taken by mouth twice a day. It can also be given through the veins by a healthcare professional, usually in a hospital setting, to treat dangerously high blood pressure. Common side effects of oral labetalol include dizziness and feeling tired. This medication is only available as a generic; brand name Trandate has been discontinued.

  • Indications of Coreg vs. Trandate

    Indications for
    •High blood pressure
    •Heart failure
    •Lower the risk of death from heart-related problems after a heart attack
    Indications for
    •High blood pressure

  • Pros and Cons of Coreg vs. Trandate

    Pros and Const for Beta blocker
    Pros
    •Taken by mouth
    •Comes as a once-daily extended-release formulation
    •Dose can be adjusted based on your response
    •Available as a lower-cost generic
    Cons
    •Need to take with food
    •Can cause you to feel more tired
    •Can cause dry eyes if you wear contact lenses
    •Shouldn't be taken if you have asthma or an asthma-related condition
    Pros and Const for Beta blocker
    Pros
    •Less likely to affect heart rate than other beta blockers
    •Less likely to cause weight gain than other beta blockers
    •Safe to take during pregnancy
    Cons
    •Causes higher risk of wheezing and breathing problems compared to selective beta-blockers
    •Need to take twice a day (and three times a day for some people)
    •Stopping the medication suddenly can worsen chest pain

  • Common Side Effects of Coreg vs. Trandate

    Common Side Effects for
    •Dizziness (6%)

    Please note: These side effects were reported by people who took carvedilol (Coreg) in clinical studies for high blood pressure.

    Common Side Effects for
    •Dizziness (11%)
    •Nausea (6%)
    •Feeling tired (5%)
    •Indigestion (3%)
    •Stuffy nose (3%)
    •Headache (2%)

  • Warnings of Coreg vs. Trandate

    Common Side Effects for
    •Worsening chest pain and heart attacks
    •Slow heart rate and low blood pressure
    •Heart failure
    •Hiding symptoms of low blood sugar
    •Risk of difficulty breathing
    •Hiding symptoms of high thyroid hormone
    •Risk of kidney problems
    •Severe allergic reactions
    •Greater risk during surgery
    •Risk of eye problems during surgery
    Common Side Effects for
    •Liver injury
    •Heart failure
    •Worsening chest pain and heart attacks
    •Risk of difficulty breathing
    •Hiding symptoms of low blood sugar
    •Greater risk during surgery
    •Risk of heart block (medication interaction)

  • Prices with our coupons for Coreg vs. Trandate

    Learn more about Carvedilol
    Learn more about Labetalol

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