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Compare Hydrochlorothiazide vs. Coreg

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Hydrochlorothiazide (Microzide) and carvedilol (Coreg) are both used to treat high blood pressure, but they belong to different medication classes and work in different ways. Hydrochlorothiazide is a diuretic, also known as a water pill, that helps you urinate more to remove extra fluid and certain electrolytes from your body. This helps lower blood pressure and reduce swelling. Carvedilol, on the other hand, is a beta blocker that lowers blood pressure by relaxing your blood vessels and slowing down your heart rate. You typically take hydrochlorothiazide once daily, while carvedilol is taken twice daily in its immediate-release form or once daily in its extended-release form. Common side effects of hydrochlorothiazide include dizziness and frequent urination, whereas carvedilol can cause dizziness, tiredness, and diarrhea. Both medications are available as lower-cost generics.

  • Hydrochlorothiazide
    Carvedilol (Coreg)
  • Hydrochlorothiazide
    Carvedilol (Coreg)

  • Summary of Hydrochlorothiazide vs. Coreg

    Summary for Diuretic (water pill)
    Prescription only

    Hydrochlorothiazide is a diuretic or water pill. It helps lower blood pressure. It also helps with swelling from fluid buildup (edema) caused by some health conditions, like heart failure and kidney problems. People of all ages can take hydrochlorothiazide tablets and capsules. But children typically take much smaller, weight-based doses. You typically take your dose by mouth once (sometimes twice) daily, but avoid nighttime dosing so you won't wake up to urinate. Some common side effects are dizziness and urinating more often.

    Summary for Beta blocker
    Prescription only

    Carvedilol (Coreg) is used to treat high blood pressure, manage heart failure, and help with heart problems after a heart attack. It belongs to the beta blocker drug class. This medication comes as a tablet that's taken by mouth twice daily, and as an oral extended-release (ER) capsule (brand name Coreg CR) that's taken once daily. Common side effects include dizziness, feeling tired, and diarrhea.

  • Indications of Hydrochlorothiazide vs. Coreg

    Indications for
    •High blood pressure
    •Swelling in the body from fluid buildup (edema)
    Indications for
    •High blood pressure
    •Heart failure
    •Lower the risk of death from heart-related problems after a heart attack

  • Pros and Cons of Hydrochlorothiazide vs. Coreg

    Pros and Const for Diuretic (water pill)
    Pros
    •Helps getting rid of extra fluid in your body
    •A first-choice treatment option if you have high blood pressure or heart failure
    •Dose can be adjusted based on how well it's working for you
    Cons
    •Can make you urinate more often
    •Can cause electrolytes and fluid levels to be out of balance, which can be dangerous
    •Might not be a good option for people with a sulfa allergy
    Pros and Const for Beta blocker
    Pros
    •Taken by mouth
    •Comes as a once-daily extended-release formulation
    •Dose can be adjusted based on your response
    •Available as a lower-cost generic
    Cons
    •Need to take with food
    •Can cause you to feel more tired
    •Can cause dry eyes if you wear contact lenses
    •Shouldn't be taken if you have asthma or an asthma-related condition

  • Common Side Effects of Hydrochlorothiazide vs. Coreg

    Common Side Effects for
    •Dizziness
    •Weakness
    •Headache
    •Blurry vision
    •Low blood pressure
    •Change in electrolyte levels
    Common Side Effects for
    •Dizziness (6%)

    Please note: These side effects were reported by people who took carvedilol (Coreg) in clinical studies for high blood pressure.

  • Warnings of Hydrochlorothiazide vs. Coreg

    Common Side Effects for
    •Low fluid and electrolyte levels in the body
    •Possibly higher calcium levels
    •Higher blood sugar
    •Risk of gout
    •Risk of vision problems and glaucoma
    •Use with caution in people with kidney problems
    Common Side Effects for
    •Worsening chest pain and heart attacks
    •Slow heart rate and low blood pressure
    •Heart failure
    •Hiding symptoms of low blood sugar
    •Risk of difficulty breathing
    •Hiding symptoms of high thyroid hormone
    •Risk of kidney problems
    •Severe allergic reactions
    •Greater risk during surgery
    •Risk of eye problems during surgery

  • Prices with our coupons for Hydrochlorothiazide vs. Coreg

    Learn more about Hydrochlorothiazide
    Learn more about Carvedilol

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