Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Hydrochlorothiazide vs. Coreg

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Hydrochlorothiazide (Microzide) and carvedilol (Coreg) are both used to treat high blood pressure, but they belong to different medication classes and work in different ways. Hydrochlorothiazide is a diuretic, also known as a water pill, that helps you urinate more to remove extra fluid and certain electrolytes from your body. This helps lower blood pressure and reduce swelling. Carvedilol, on the other hand, is a beta blocker that lowers blood pressure by relaxing your blood vessels and slowing down your heart rate. You typically take hydrochlorothiazide once daily, while carvedilol is taken twice daily in its immediate-release form or once daily in its extended-release form. Common side effects of hydrochlorothiazide include dizziness and frequent urination, whereas carvedilol can cause dizziness, tiredness, and diarrhea. Both medications are available as lower-cost generics.

  • Hydrochlorothiazide
    Carvedilol (Coreg)
  • Hydrochlorothiazide
    Carvedilol (Coreg)

  • Summary of Hydrochlorothiazide vs. Coreg

    Summary for Diuretic (water pill)
    Prescription only

    Hydrochlorothiazide is a water pill that helps to lower blood pressure and ease swelling from fluid (edema) caused by many health conditions, such as heart failure and kidney problems. Typically, you take hydrochlorothiazide by mouth once (sometimes twice) daily. Some common side effects of hydrochlorothiazide include dizziness and urinating more often.

    Summary for Beta blocker
    Prescription only

    Carvedilol (Coreg) is used to treat high blood pressure, manage heart failure, and help with heart problems after a heart attack. It belongs to the beta blocker drug class. This medication comes as a tablet that's taken by mouth twice daily, and as an oral extended-release (ER) capsule (brand name Coreg CR) that's taken once daily. Common side effects include dizziness, feeling tired, and diarrhea.

  • Indications of Hydrochlorothiazide vs. Coreg

    Indications for
    •High blood pressure
    •Swelling in the body from fluids (edema), in addition to other medications
    Indications for
    •High blood pressure
    •Heart failure
    •Lower the risk of death from heart-related problems after a heart attack

  • Pros and Cons of Hydrochlorothiazide vs. Coreg

    Pros and Const for Diuretic (water pill)
    Pros
    •Does a good job getting rid of extra fluids in your body
    •A first choice treatment option if you have high blood pressure and heart failure
    •Provider can adjust dose based on your response
    •Might protect against osteoporosis over time since it raises the body's level of calcium
    Cons
    •Makes you urinate more often
    •Must be used with caution in people with severe kidney or liver problems
    •Raises risk of gout attacks in people with poor kidney function or a history of gout
    •Can cause electrolytes and fluid levels to be out of balance, which can be dangerous
    Pros and Const for Beta blocker
    Pros
    •Taken by mouth
    •Comes as a once-daily extended-release formulation
    •Dose can be adjusted based on your response
    •Available as a lower-cost generic
    Cons
    •Need to take with food
    •Can cause you to feel more tired
    •Can cause dry eyes if you wear contact lenses
    •Shouldn't be taken if you have asthma or an asthma-related condition

  • Common Side Effects of Hydrochlorothiazide vs. Coreg

    Common Side Effects for
    •Dizziness
    •Weakness
    •Skin more sensitive to sunlight
    •Temporary blurred vision
    •Headache
    •Low blood pressure
    •Electrolytes out of balance
    •Difficulty getting or maintaining an erection
    Common Side Effects for
    •Dizziness (6%)

    Please note: These side effects were reported by people who took carvedilol (Coreg) in clinical studies for high blood pressure.

  • Warnings of Hydrochlorothiazide vs. Coreg

    Common Side Effects for
    •Vision problems
    •Fluid and electrolyte imbalance
    •Waste build up in body
    •Higher blood sugars
    •Gout
    •Allergic reaction
    Common Side Effects for
    •Worsening chest pain and heart attacks
    •Slow heart rate and low blood pressure
    •Heart failure
    •Hiding symptoms of low blood sugar
    •Risk of difficulty breathing
    •Hiding symptoms of high thyroid hormone
    •Risk of kidney problems
    •Severe allergic reactions
    •Greater risk during surgery
    •Risk of eye problems during surgery

  • Prices with our coupons for Hydrochlorothiazide vs. Coreg

    Learn more about Hydrochlorothiazide
    Learn more about Carvedilol

Compare other Heart Failure and Hypertension drugs

Catapres vs HydrochlorothiazideEnalapril vs HydrochlorothiazideFelodipine vs HydrochlorothiazideHydrochlorothiazide vs CoregHydrochlorothiazide vs DigoxinHydrochlorothiazide vs DutoprolHydrochlorothiazide vs EdecrinHydrochlorothiazide vs PrazosinHydrochlorothiazide vs SpironolactoneHydrochlorothiazide vs TenoreticHydrochlorothiazide vs ZiacLosartan vs HydrochlorothiazideNifedipine vs HydrochlorothiazidePropranolol vs HydrochlorothiazideZestoretic vs HydrochlorothiazideEnalapril vs AltaceEnalapril vs AtacandEnalapril vs AvaproEnalapril vs BenicarEnalapril vs ChlorthalidoneExforge vs TenoreticHydralazine vs DigoxinIsordil vs DigoxinLisinopril vs DigoxinLopressor vs TenoreticSpironolactone vs DigoxinTenoretic vs DutoprolTenoretic vs HyzaarTenoretic vs Lopressor HctTenoretic vs Ziac
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.