provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content
Atenolol / Chlorthalidone Coupon - Atenolol / Chlorthalidone 50mg/25mg tablet

atenolol / chlorthalidone

Generic Tenoretic
Used for Hypertension
Used for Hypertension

Tenoretic (atenolol / chlorthalidone) is used to lower blood pressure in adults. It's a combination of two types of blood pressure medications: a beta blocker (atenolol) and a diuretic (chlorthalidone). The tablet is taken by mouth once daily. Side effects, like dizziness and tiredness, are usually mild and they get better over time. Tenoretic (atenolol / chlorthalidone) is available as a brand-name and generic medication.

Last reviewed on March 13, 2025
basics-icon

What is Tenoretic (atenolol / chlorthalidone)?

What is Tenoretic (atenolol / chlorthalidone) used for?

How Tenoretic (atenolol / chlorthalidone) works

Tenoretic (atenolol / chlorthalidone) is a combination of two different medications that both help lower blood pressure.

  • Atenolol is a beta blocker. It works by blocking certain chemicals from attaching to beta receptors on the heart. This slows down your heart rate and lowers your blood pressure.

  • Chlorthalidone is a thiazide-like diuretic (water pill). It works in the kidneys and moves extra water and salts into your urine. This helps remove extra water from your body. This then helps lowers blood pressure.

Are you looking for information on atenolol (Tenormin) or chlorthalidone (Thalitone) instead?
When does Tenoretic (atenolol / chlorthalidone) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsTenoretic
Drug ClassBeta blocker / Diuretic (water pill)
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
coupon-save-icon

Get your GoodRx coupon

Avg retail price
$99.890
GoodRx discount
$99.89
See prices
basics-icon

What are the side effects of Tenoretic (atenolol / chlorthalidone)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Atenolol:
  • Dizziness
  • Tiredness
  • Nausea
  • Slow heartbeat
Chlorthalidone:
  • Dizziness when standing up too quickly
  • Stomach irritation or cramps
  • Nausea
  • Constipation

Other Side Effects

Note: The side effects of Tenoretic are similar to those of its two individual medications (atenolol and chlorthalidone).

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe allergic reaction: trouble breathing; swelling of the tongue, mouth, or throat; hives
  • Heart problems: trouble breathing; tiredness; chest pain; irregular heartbeat; can't walk very far before feeling out of breath; swelling in the legs, ankles, or feet;
  • Trouble breathing: tightness in the chest, trouble catching your breath, wheezing, cough, dizziness, extreme tiredness

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Cold arms or legs

difficult or labored breathing

shortness of breath

tightness in chest

wheezing

Less common

Chest pain or discomfort

chills

cold sweats

confusion

dizziness, faintness, or lightheadedness when getting up from lying or sitting position

leg pain

lightheadedness, dizziness, or fainting

slow or irregular heartbeat

unusual tiredness or weakness

Incidence not determined

Black, tarry stools

bleeding gums

blood in urine or stools

feeling that others are watching you or controlling your behavior

feeling that others can hear your thoughts

fever

general feeling of discomfort, illness, or weakness

paleness or cold feeling in fingertips and toes

pinpoint red spots on skin

seeing, hearing, or feeling things that are not there

severe mood or mental changes

skin irritation or rash, including rash that looks like psoriasis

tingling or pain in fingers or toes when exposed to cold

unusual behavior

unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Blurred vision

decreased urination

dry mouth

increase in heart rate

muscle cramps or pain

numbness, tingling, pain, or weakness in hands or feet

rapid breathing

seizures

sunken eyes

sweating

thirst

trembling

weakness and heaviness of legs

wrinkled skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Discouragement

feeling sad or empty

irritability

lack of appetite

loss of interest or pleasure

tiredness

trouble concentrating

trouble sleeping

Less common

Diarrhea

feeling of constant movement of self or surroundings

nausea

sensation of spinning

unusual drowsiness, dullness, or feeling of sluggishness

Incidence not determined

Decreased interest in sexual intercourse

disturbed color perception

double vision

hair loss, thinning of hair

halos around lights

headache

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

loss of vision

night blindness

overbright appearance of lights

pain of penis on erection

tunnel vision

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Tenoretic (atenolol / chlorthalidone)

thumbs-up

Pros

Combines two medications into one pill to help lower blood pressure better

Only need to take once a day

Can take with or without food

Gets rid of extra fluids in your body

thumbs-down

Cons

Might make you urinate more often

Comes in fixed doses, which makes it hard to adjust the dose if needed

Not safe if you're pregnant or breastfeeding

Might cause an allergic reaction if you have a sulfa allergy

pharmacist-tips

Pharmacist tips for Tenoretic (atenolol / chlorthalidone)

pharmacist
  • Take Tenoretic (atenolol / chlorthalidone) in the morning or early afternoon. This medication can make you urinate more. So taking it earlier in the day can help you avoid waking up at night often to use the bathroom.

    • If you're checking your blood pressure at home, record your measurements. Bring your log to your follow-up appointments so your prescriber can see how well Tenoretic (atenolol / chlorthalidone) is working for you. They can see if you need any changes to your treatment plan to manage your blood pressure better.

      • Tenoretic (atenolol / chlorthalidone) might make you feel more tired or out of breath while you're exercising or going about your usual life. This usually gets better as you get used to the medication. But talk to your prescriber if this side effect doesn't seem go away.

        • Don't forget to use sunscreen whenever you go outside even if it's cloudy. Tenoretic (atenolol / chlorthalidone) can make your skin more sensitive to sunlight. This can raise your risk for sunburns.

          • You might need to get blood tests or urine tests while you're taking Tenoretic (atenolol / chlorthalidone). These tests help your prescriber check your kidney health and electrolyte levels. Get your labs done on time so they can make sure it's safe for you to continue taking this medication.

            • Tell your prescriber if you've ever had to use a life-saving medication like epinephrine (EpiPen) for an allergic reaction. Tenoretic (atenolol / chlorthalidone) can interact with these medications and make them work less well.

              • If you have a planned surgery coming up, tell the surgery team that you're taking Tenoretic (atenolol / chlorthalidone). They'll know to keep a close eye on your heart rate during the surgery to keep you safe.

                • Don't stop taking Tenoretic (atenolol / chlorthalidone) suddenly without talking to your prescriber. Stopping the medication too abruptly can be harmful because it can make your blood pressure go up. It can also raise your risk of serious heart problems like chest pain or heart attack. Your prescriber can give your directions on how to stop the medication safely.

                  More on Tenoretic (atenolol / chlorthalidone) tips

                  faqs

                  Frequently asked questions about Tenoretic (atenolol / chlorthalidone)

                  Is Tenoretic (atenolol / chlorthalidone) an ACE inhibitor?
                  No. Tenoretic (atenolol / chlorthalidone) isn't an angiotensin-converting enzyme (ACE) inhibitor. Instead, it contains a beta blocker and a thiazide diuretic (water pill). ACE inhibitors, beta blockers, and diuretics all help lower blood pressure. But they work in different ways.
                  How fast does it take for Tenoretic (atenolol / chlorthalidone) to work?
                  Atenolol, one of the ingredients in Tenoretic, can start to lower heart rate within 1 hour. It reaches its strongest effect on heart rate in about 2 to 4 hours. Heart rate and blood pressure are closely linked. In general, most blood pressure medications take a few hours to lower blood pressure after you take them. But it can take a couple weeks of treatment to see a consistent reduction in blood pressure. Ask your prescriber if you have questions about how long it takes Tenoretic (atenolol / chlorthalidone) to lower your blood pressure.
                  Does Tenoretic (atenolol / chlorthalidone) cause weight gain?
                  Weight gain wasn't a reported side effect of Tenoretic (atenolol / chlorthalidone) during clinical studies. If you notice weight changes that concern you while taking this medication, talk to your healthcare professional. They can help you find out what's causing it and how to manage it.
                  Can I crush Tenoretic (atenolol / chlorthalidone)?
                  The manufacturer doesn't say whether or not you can safely crush Tenoretic (atenolol / chlorthalidone). Talk to your prescriber or pharmacist about what to do if you're having trouble swallowing the tablet whole.
                  Can you drink alcohol with Tenoretic (atenolol / chlorthalidone)?
                  It's recommended to avoid alcohol while you're taking Tenoretic (atenolol / chlorthalidone). Alcohol can make blood pressure medications work less well. It can also raise your risk for side effects, like dizziness and stomach upset. Talk to a healthcare professional about your drinking habits while taking this medication.
                  Does Tenoretic (atenolol / chlorthalidone) make you urinate more?
                  Yes. This medication contains chlorthalidone, which is a diuretic (water pill). Diuretics can make you urinate more. This helps your body get rid of extra fluid (water) to lower your blood pressure. Taking Tenoretic (atenolol / chlorthalidone) during the day rather than at night can help you avoid waking up often to urinate.
                  Can I take Mucinex with Tenoretic (atenolol / chlorthalidone)?
                  It depends on the Mucinex product. Mucinex is a branded line of products. And each Mucinex product can have different ingredients in them. You can take Mucinex that only has guaifenesin with Tenoretic (atenolol / chlorthalidone). It shouldn't affect your blood pressure or the way the medications work. But some Mucinex products contain pseudoephedrine, which can raise blood pressure. Check the label and ask a pharmacist if the ingredients are safe to take with your blood pressure medication.
                  Can you take Tenoretic (atenolol / chlorthalidone) while pregnant or breastfeeding?
                  If you're pregnant, thinking of becoming pregnant, or breastfeeding, talk to your prescriber or obstetrician-gynecologist (OB-GYN). Tenoretic (atenolol / chlorthalidone) can cause harm to an unborn baby, like growth problems, if taken during pregnancy. It can also pass into breast milk and slow your baby's heart rate if you're breastfeeding. Discuss the risks and benefits with your care team. They can help find safer options to manage blood pressure during pregnancy or while breastfeeding. If you become pregnant while taking Tenoretic (atenolol / chlorthalidone), call your prescriber right away.
                  GoodRxEducationalIcon

                  How to save using GoodRx

                  Compare Prices
                  1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
                  Select your free coupon
                  2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
                  Show coupon to your pharmacist
                  3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
                  Get free couponLearn more
                  warings-icon

                  What are the risks and warnings for Tenoretic (atenolol / chlorthalidone)?

                  Tenoretic (atenolol / chlorthalidone) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Risk of heart problems after stopping Tenoretic (atenolol / chlorthalidone) suddenly

                  • Risk factors: Stopping Tenoretic (atenolol / chlorthalidone) suddenly | Coronary artery disease

                    Don’t stop taking Tenoretic (atenolol / chlorthalidone) suddenly. It can raise your risk of serious heart problems, like chest pain or heart attack.

                    Get medical help right away if you have chest tightness, chest pain that spreads to your arms and neck, shortness of breath, dizziness, and fatigue. These can be signs of serious heart problems.

                    If you need to stop taking Tenoretic (atenolol / chlorthalidone) for any reason, talk to your prescriber first. They can help lower your dose safely over about a week or so before stopping completely.

                    risk-warning

                    Risk of heart failure

                    • Risk factors: Congestive heart failure

                      In some cases, Tenoretic (atenolol / chlorthalidone) might raise the risk of heart failure. This is because beta blockers (like the atenolol in Tenoretic) can slow down your heart. This can cause your heart muscle to pump less often. If you already have heart failure, your healthcare professional (HCP) will only prescribe this medication if they believe the benefits outweigh the risks. They might follow up with you more often during treatment.

                      Talk to your HCP if you notice signs of heart failure. Watch for swelling in your feet or ankles, fast or irregular pulse, or shortness of breath when you lie down.

                      risk-warning

                      Risk of heart block when taken with calcium channel blockers

                      • Risk factors: Taking calcium channel blockers | Currently have or have had heart rhythm problems or other heart problems

                        Let your prescriber know if you're taking any calcium channel blockers, like verapamil or diltiazem (Cardizem). Taking these medications with Tenoretic (atenolol / chlorthalidone) can slow your heartbeat or cause heart block, which can be dangerous. Share a list of all your medications with your prescriber so they can help check for interactions.

                        risk-warning

                        Caution use in people with breathing problems

                        • Risk factors: History of asthma | History of chronic obstructive pulmonary disease (COPD) | History of lung problems

                          Tell your prescriber if you have any breathing problems, like asthma. Beta blocker medications, like Tenoretic (atenolol / chlorthalidone), can cause the airways in your lungs to tighten. This can make it harder to breathe for people with lung problems.

                          Tenoretic (atenolol / chlorthalidone) has a lower chance of causing breathing problems than some other beta blockers because atenolol mainly affects the heart. But you should still be aware of this risk. Keep a rescue inhaler nearby in case you have sudden trouble breathing if you have lung problems.

                          risk-warning

                          Kidney problems

                          • Risk factors: History of kidney problems

                            Your body gets rid of Tenoretic (atenolol / chlorthalidone) using your kidneys. If your kidneys aren't working well, more medication can build up in your body and lead to side effects. Additionally, Tenoretic (atenolol / chlorthalidone) can sometimes cause certain waste products to build up.

                            Let your HCP know if you have a history of kidney problems. They might check your kidney function more often. In some cases, they might need to adjust your dose of Tenoretic (atenolol / chlorthalidone) to keep you safe.

                            risk-warning

                            Changes in fluids and electrolytes in the body

                            • Risk factors: History of kidney or liver problems | Dehydration

                              Tenoretic (atenolol / chlorthalidone) can make your body lose fluids. It can also cause changes to the levels of your electrolytes, like potassium, sodium, and chloride. Your risk might be higher if you have kidney problems. And if you have liver problems, small changes in fluid and electrolyte levels can raise your risk for liver complications.

                              Tell your care team if you have dry mouth, weakness, muscle cramps, tiredness, fast or irregular heart rate, nausea, or vomiting. These can be signs of abnormal electrolyte levels. Your HCP might have you get regular blood work to check your electrolyte levels while taking Tenoretic (atenolol / chlorthalidone).

                              risk-warning

                              Hidden symptoms of low blood sugar

                              • Risk factors: Diabetes | Fasting (e.g., related to getting surgery, not eating regularly, vomiting)

                                There's a risk that the atenolol in Tenoretic can make it harder for you to notice signs of low blood sugar. Some signs, such as fast heartbeat, tremors, and irritability, might not be as noticeable. Sweating might be the only sign you have warning you of low blood sugar levels. This is especially important people with diabetes to know. Speak with your HCP about when and how to check your blood sugar if you start Tenoretic (atenolol / chlorthalidone).

                                risk-warning

                                Hidden symptoms of overactive thyroid

                                • Risk factors: Hyperthyroidism

                                  If you have hyperthyroidism (too much thyroid hormone), talk to your HCP before stopping Tenoretic (atenolol / chlorthalidone). This medication can hide signs of hyperthyroidism, like a fast heart rate. Suddenly stopping the medication can worsen symptoms of hyperthyroidism. It can also lead to a serious condition called a "thyroid storm," which can cause high fever and rapid heartbeat.

                                  risk-warning

                                  Possible gout

                                  • Risk factors: History of gout

                                    The chlorthalidone component of Tenoretic can raise the uric acid levels in your body. This can sometimes lead to gout. Make sure to tell your prescriber if you've had a history of gout before starting this medication. They can tell you what signs to look out for, such as swollen, red, and painful joints.

                                    risk-warning

                                    Risk of harm to baby

                                    • Risk factors: Pregnant | Breastfeeding

                                      Taking Tenoretic (atenolol / chlorthalidone) during pregnancy or while breastfeeding can possibly harm your baby. If you're pregnant, thinking of becoming pregnant, or breastfeeding, talk to your prescriber or obstetrician-gynecologist (OB-GYN) about the risks and benefits. They can help find a safer option for you.

                                      dosage

                                      Tenoretic (atenolol / chlorthalidone) dosage forms

                                      The average cost for 90 tablets of 50mg/25mg of Tenoretic (atenolol / chlorthalidone) is $1085.98 with a free GoodRx coupon. This is 15.78% off the average retail price of $1289.43.
                                      tablet
                                      Tablet
                                      DosageQuantityPrice as low asPrice per unit
                                      50mg/25mg90 tablets$1085.98$12.07
                                      100mg/25mg30 tablets$158.71$5.29

                                      Typical dosing for Tenoretic (atenolol / chlorthalidone)

                                      The typical starting dose is 50 mg/25 mg (atenolol/chlorthalidone) by mouth once daily. Your prescriber might raise your dose slowly over time if you need more help with managing your blood pressure.

                                      The maximum recommended dose is 100 mg/25 mg (atenolol/chlorthalidone) once daily.

                                      Your dose might differ if you have kidney problems.

                                      interactions

                                      Interactions between Tenoretic (atenolol / chlorthalidone) and other drugs

                                      Tenoretic (atenolol / chlorthalidone) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Tenoretic (atenolol / chlorthalidone). Please note that only the generic name of each medication is listed below.

                                      Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                      Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                      drug-cost

                                      How much does Tenoretic (atenolol / chlorthalidone) cost?

                                      To access savings, use a GoodRx coupon and pay just a fraction of the retail price.View prices & coupons
                                      contraindications-icon

                                      Tenoretic (atenolol / chlorthalidone) contraindications

                                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Tenoretic (atenolol / chlorthalidone) will not be safe for you to take.
                                      alternatives

                                      What are alternatives to Tenoretic (atenolol / chlorthalidone)?

                                      There are a number of medications that your doctor can prescribe in place of Tenoretic (atenolol / chlorthalidone). Compare a few possible alternatives below.
                                      Tenoretic (atenolol / chlorthalidone)
                                      $99.89 Lowest GoodRx priceView Prices
                                      images

                                      Tenoretic (atenolol / chlorthalidone) images

                                      White Round M 63 - Atenolol / Chlorthalidone 50mg-25mg Tablet
                                      This medicine is White, Round, Scored Tablet Imprinted With "M 63".White Round M 63 - Atenolol / Chlorthalidone 50mg-25mg Tablet
                                      White Round Dan 5782 - Atenolol / Chlorthalidone 50mg-25mg Tablet
                                      This medicine is White, Round, Scored Tablet Imprinted With "Dan 5782".White Round Dan 5782 - Atenolol / Chlorthalidone 50mg-25mg Tablet
                                      White Round 11 67 - Atenolol / Chlorthalidone 50mg-25mg Tablet
                                      This medicine is White, Round, Scored Tablet Imprinted With "11 67".White Round 11 67 - Atenolol / Chlorthalidone 50mg-25mg Tablet
                                      Pink Round U And 2 7 - Atenolol / Chlorthalidone 50mg-25mg Tablet
                                      This medicine is Pink, Round, Scored Tablet Imprinted With "2 7" And "U".Pink Round U And 2 7 - Atenolol / Chlorthalidone 50mg-25mg Tablet

                                      Get savings updates for Tenoretic (atenolol / chlorthalidone)

                                      Receive price alerts, news, and other messages from GoodRx about Tenoretic (atenolol / chlorthalidone) and other healthcare topics and relevant savings offers.

                                      By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.

                                      References

                                      Best studies we found

                                      ANI Pharmaceuticals, Inc. (2024). Atenolol and chlorthalidone tablet [package insert]. DailyMed.

                                      MedlinePlus. (2023). Uric acid - blood.

                                      MedlinePlus. (2024). Pheochromocytoma.

                                      View All References (3)

                                      MedlinePlus. (2024). Thyroid storm.

                                      National Heart, Lung, and Blood Institute. (2022). What is cardiogenic shock?

                                      Vue, M. H., et al. (2011). Drug-induced glucose alterations part 1: Drug-induced hypoglycemia. Diabetes Spectrum.

                                      GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
                                      Was this page helpful?

                                      Browse medications

                                      View All

                                      Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.