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Lasix vs. Inspra

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Furosemide (Lasix) and eplerenone (Inspra) are both medications used to treat high blood pressure, but they belong to different medication classes. Furosemide is a loop diuretic, often called a water pill, that helps your body get rid of extra fluid and electrolytes, which can also help with swelling. Eplerenone, on the other hand, is an aldosterone receptor antagonist that works by blocking a hormone that raises blood pressure, helping your body remove extra salt and water. Furosemide is available as a generic and comes in tablet and oral solution forms, while eplerenone is available as a generic tablet. Furosemide is typically taken once or twice daily, while eplerenone is usually taken once daily. Common side effects of furosemide include increased urination and dizziness, while eplerenone can cause digestive issues and high potassium levels. Furosemide can interact with medications like corticosteroids, while eplerenone can interact with ACE inhibitors and NSAIDs. Both medications require careful monitoring, but they have different risks and benefits based on your health needs.

Furosemide

(Lasix)

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Eplerenone

(Inspra)

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Summary for Lasix

Prescription only

Furosemide (Lasix) is a loop diuretic, a type of water pill. Furosemide (Lasix) is used to relieve swelling from extra fluids in children and adults. This medication can also lower blood pressure, though it's not a first-choice option for this condition. Furosemide (Lasix) comes as a tablet that's taken by mouth, typically once or twice daily. It's also available as an oral solution for people who've trouble swallowing tablets. Furosemide (Lasix) will cause you to urinate more often as a side effect, so it's best to not take this medication too close to bedtime.

Indications for Lasix

  • Swelling (edema) due to heart failure, liver problems, or kidney problems
  • High blood pressure

Pros and Cons for Lasix

Pros

  • Starts working within an hour after you take it
  • Available in liquid form for children or people who have trouble swallowing pills
  • Available as a lower-cost generic medication

Cons

  • Not a good choice for people with a sulfa allergy
  • Might cause you to urinate in the middle of the night if you take it later in the day
  • Can make you more dizzy and raise your risk for falling down

Common Side Effects for Lasix

  • Urinating more often
  • Dizziness
  • Headache
  • Feeling off balance when you get up suddenly
  • Skin sensitive to the sun

Warnings for Lasix

  • Dehydration and electrolyte imbalance
  • Caution in people with liver problems
  • Hearing problems
  • Problems with urination
  • Allergic reaction
  • Gout

Summary for Inspra

Prescription only

Eplerenone (Inspra) is a medication that’s used to treat high blood pressure and improve survival among people with heart failure after a heart attack. It comes as an oral tablet that can be taken alone or in combination with other medications. Look out for side effects including dizziness, nausea, cough, and shortness of breath. Eplerenone (Inspra) is available as a generic tablet and also under the brand name Inspra.

Indications for Inspra

  • Heart failure after a heart attack
  • High blood pressure

Pros and Cons for Inspra

Pros

  • Improves survival for people with heart failure after a heart attack
  • Fewer side effects than spironolactone
  • Typically once daily dosing

Cons

  • Have to get regular blood tests while taking the medication to check for high potassium levels
  • Not safe to use with severe kidney problems
  • Isn’t a first-choice medication for high blood pressure or heart failure

Common Side Effects for Inspra

  • Digestive system problems (20%)
  • Nervous system problems (15%)
  • Urinary tract problems (14%)
  • Shortness of breath (7%)
  • Skin problems (7%)
  • Mental health problems (7%)
  • Cough (5%)

Warnings for Inspra

  • High potassium (hyperkalemia)

Prices with our coupons for Lasix vs. Inspra

Price Card Drug Icon
Furosemide30 tablets / 20mg
$4.00$4.00
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Price Card Drug Icon
Eplerenone30 tablets / 25mg
$23.53$91.02
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