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Compare Multaq vs. Amiodarone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Multaq (dronedarone)
    Amiodarone (Pacerone)
  • Multaq (dronedarone)
    Amiodarone (Pacerone)

  • Summary of Multaq vs. Amiodarone

    Summary for Antiarrhythmic
    Prescription only

    Multaq (dronedarone) is an antiarrhythmic medication. It's used to lower the risk of hospitalization in adults with atrial fibrillation (AFib). Multaq (dronedarone) comes as a tablet that's taken by mouth twice per day, preferably with food. Common side effects of this medication include diarrhea, nausea, and stomach pain. Multaq (dronedarone) is brand-name only and not available as a generic.

    Summary for Antiarrhythmic
    Prescription only

    Amiodarone (Pacerone) is an antiarrhythmic medication. It's FDA-approved to treat life-threatening ventricular fibrillation and fast heart rate (tachycardia) in adults who either can't take it or whose condition isn't well-controlled by other antiarrhythmics. It's sometimes prescribed off-label for atrial fibrillation (AFib). Amiodarone (Pacerone) comes as tablets that are taken by mouth. The total daily dose can be taken once per day, or split into smaller doses and taken throughout the day to prevent stomach-related side effects, like nausea and vomiting.

  • Indications of Multaq vs. Amiodarone

    Indications for
    •To lower the risk of hospitalization from atrial fibrillation (AFib) in adults who have a history of paroxysmal or persistent AFib
    Indications for
    •Life-threatening ventricular fibrillation that keeps coming back (when other antiarrhythmics haven't worked well)
    •Life-threatening tachycardia that keeps coming back (when other antiarrhythmics haven't worked)

  • Pros and Cons of Multaq vs. Amiodarone

    Pros and Const for Antiarrhythmic
    Pros
    •Lowers the risk of hospitalization from AFib
    •Prescribed in one standard dose; no dose adjustments needed
    •Taken by mouth
    Cons
    •Not safe for use in heart failure, permanent AFib, or during pregnancy
    •Taken twice daily
    •Interacts with many medications and supplements
    Pros and Const for Antiarrhythmic
    Pros
    •Works well to treat certain heart rate and rhythm problems
    •Can be taken with or without food
    •Can be taken once daily (as long as you're tolerating the medication and the total daily dose is less than 1,000 mg)
    Cons
    •Stays in the body for many weeks
    •Not for people with iodine allergy
    •Only available as a 200 mg tablet, so you might need to take several tablets depending on your dose

  • Common Side Effects of Multaq vs. Amiodarone

    Common Side Effects for
    •Rise in creatinine levels (51%)
    •Abnormal heart rhythm (QTc prolongation) (28%)
    •Diarrhea (9%)
    •Weakness (7%)
    •Nausea (5%)
    •Skin reactions, including rash and itching (5%)
    Common Side Effects for
    •Nausea
    •Vomiting
    •Constipation
    •Poor appetite
    •Stomach pain
    •More sensitive to the sun
    •Feeling unwell
    •Fatigue
    •Tremor or abnormal movement
    •Poor coordination
    •Difficulty walking
    •Dizziness
    •Pins and needles sensation in the skin
    •Lower sex drive
    •Difficulty sleeping
    •Headache
    •Change in vision
    •Lung inflammation or scarring
    •Flushing
    •Change in taste or smell
    •Excess fluid under the skin (edema)
    •Abnormal saliva production
    •Abnormal blood clotting

  • Warnings of Multaq vs. Amiodarone

    Common Side Effects for
    •Not safe for people with severe heart failure or permanent atrial fibrillation
    •New or worsening heart failure
    •Liver damage
    •Lung damage
    •Low potassium and magnesium levels
    •Life-threatening abnormal heart rhythm
    •Kidney damage or failure
    •Harm to unborn babies
    Common Side Effects for
    •Arrhythmia (abnormal heartbeat)
    •Lung damage
    •Liver damage
    •Vision problems
    •Thyroid problems
    •Slow heartbeat
    •Effects on heart devices
    •Harm to unborn babies
    •Nerve problems

  • Prices with our coupons for Multaq vs. Amiodarone

    Learn more about Multaq
    Learn more about Amiodarone

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