Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Metoprolol succinate (Toprol XL) and sotalol (Betapace) are both medications used to treat heart conditions, but they have different uses and properties. Metoprolol succinate is a selective beta blocker primarily used to treat high blood pressure, chest pain, and to lower the risk of hospitalization and death in heart failure. It is taken once daily and is available in both generic and brand name forms. On the other hand, sotalol is a non-selective beta blocker and potassium channel blocker used to treat and prevent certain heart rhythm problems like atrial fibrillation. Sotalol is typically taken twice daily and also comes in both generic and brand name forms. Unlike metoprolol, starting sotalol usually requires a hospital stay for monitoring due to the risk of serious side effects. Both medications can cause dizziness and tiredness, but sotalol has a higher risk of causing breathing problems and requires careful monitoring of heart rhythm. Additionally, metoprolol needs to be taken with food, while sotalol can be taken with or without food but should be consistent.
Metoprolol succinate (Toprol XL)
Sotalol (Betapace)
Metoprolol succinate (Toprol XL)
Sotalol (Betapace)
Summary of Toprol XL vs. Betapace
Summary for Beta blocker
Prescription only
Metoprolol succinate (Toprol XL) is used to treat hypertension and to control chronic (long-term) chest pain. It's also used to lower the risk for hospitalization and death in people with heart failure. Metoprolol succinate (Toprol XL) is the extended-release version of metoprolol tartrate (Lopressor), but keep in mind the two versions don't treat the exact same conditions. And because metoprolol succinate (Toprol XL) is longer-acting, it's taken by mouth typically taken just once daily. Some common side effects of metoprolol succinate (Toprol XL) include tiredness or dizziness.
Summary for Antiarrhythmic
Prescription only
Sotalol (Betapace) is used to treat and prevent certain types of heart rate and heart rhythm problems (like atrial fibrillation or Afib). It's taken by mouth, typically twice a day. Usually, you need to start this medication in the hospital and stay there for at least 3 days so that the healthcare team can monitor your heart rhythm and check for any serious side effects. Sotalol (Betapace) can interact with several medications, including certain blood pressure medications and antacids. Sotalol is available both generic and brand name medications.
Indications of Toprol XL vs. Betapace
Indications for
•High blood pressure
•Chest pain (angina)
•Lower the risk of hospitalization and death in heart failure