Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Sotalol (Betapace) and bisoprolol (Zebeta) are both beta blockers, but they have some key differences. Sotalol is a non-selective beta blocker and potassium channel blocker used to treat and prevent certain heart rhythm problems like atrial fibrillation. It requires close monitoring in a hospital when you first start taking it. Bisoprolol, on the other hand, is a selective beta blocker primarily used to treat high blood pressure and is usually taken once a day. Sotalol can cause serious side effects like abnormal heart rhythms and breathing problems, especially in people with asthma or COPD. Bisoprolol is less likely to cause breathing issues but can still worsen heart failure if not managed properly. Both medications are available in generic forms, but bisoprolol is not a first-choice treatment for high blood pressure and is typically used when other medications aren't effective. Additionally, bisoprolol can interact with alcohol, increasing the risk of dizziness and fainting.
Sotalol (Betapace)
Bisoprolol
Sotalol (Betapace)
Bisoprolol
Summary of Betapace vs. Zebeta
Summary for Antiarrhythmic
Prescription only
Sotalol (Betapace) is used to treat and prevent certain types of heart rate and heart rhythm problems (like atrial fibrillation or Afib). It's taken by mouth, typically twice a day. Usually, you need to start this medication in the hospital and stay there for at least 3 days so that the healthcare team can monitor your heart rhythm and check for any serious side effects. Sotalol (Betapace) can interact with several medications, including certain blood pressure medications and antacids. Sotalol is available both generic and brand name medications.
Summary for Beta blocker
Prescription only
Bisoprolol, or bisoprolol fumarate, is a tablet that's used to treat high blood pressure. It belongs to a group of medications called beta blockers. It's usually only given when first-choice blood pressure medications aren't working well enough. Some common side effects of bisoprolol include headache, feeling tired, and diarrhea. It has some interactions with alcohol and taking bisoprolol with alcohol can worsen dizziness and raise the risk for fainting.