Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Sotalol (Betapace) and quinidine are both antiarrhythmic medications used to treat heart rhythm problems, such as atrial fibrillation or flutter. However, they belong to different classes and have distinct mechanisms of action. Sotalol is a non-selective beta blocker and potassium channel blocker, while quinidine works by blocking sodium channels. Both medications are available as a lower-cost generic. Sotalol is typically taken twice a day, while quinidine is taken every 6 to 8 hours, depending on the formulation. Common side effects of sotalol include tiredness and dizziness, while quinidine often causes diarrhea and upset stomach. Both medications require careful monitoring due to potential serious side effects, but quinidine is less commonly used today because there are better alternatives. Sotalol can interact with antacids and certain blood pressure medications, while quinidine has many drug interactions that can affect its levels in the body.
Sotalol (Betapace)
Quinidine
Sotalol (Betapace)
Quinidine
Summary of Betapace vs. Cin-Quin
Summary for Antiarrhythmic
Prescription only
Sotalol (Betapace) is used to treat and prevent certain types of heart rate and heart rhythm problems (like atrial fibrillation or Afib). It's taken by mouth, typically twice a day. Usually, you need to start this medication in the hospital and stay there for at least 3 days so that the healthcare team can monitor your heart rhythm and check for any serious side effects. Sotalol (Betapace) can interact with several medications, including certain blood pressure medications and antacids. Sotalol is available both generic and brand name medications.
Summary for Antiarrhythmic
Prescription only
Quinidine is one of the oldest antiarrhythmic medications, but isn't used as often these days since there are better alternatives.