Multaq Dosages for Adults: Your GoodRx Guide

Multaq (dronedarone) is an oral prescription antiarrhythmic medication. It can help regulate heart rhythm for adults living with atrial fibrillation (AFib). Multaq works by blocking potassium channels in your heart. This slows down the heart’s electrical activity, helping your heart to beat at a normal rhythm.

As with any medication, it’s important to take the right dosage in order for Multaq to work safely and effectively. And while Multaq doesn’t typically require any dosage adjustments, other questions may arise. Maybe you forgot a dose and are looking to get back on track. Or perhaps you took an extra dose by mistake and are wondering what to do next. You’ll find those answers and more here in this Multaq dosage guide.

What’s the typical Multaq dosage?

The typical Multaq dosage is 400 mg by mouth twice daily, with your morning and evening meals. Taking it with food helps your body absorb the medication better. But avoid taking Multaq with grapefruit or grapefruit juice. These food items can increase levels of Multaq in your body and raise your risk of side effects, such as diarrhea or nausea.

Note: Multaq is only FDA approved for use in adults 18 years of age and older. Because of this, there’s no standard Multaq dosage for children. If your child has AFib, please follow their cardiology care team’s recommendations for treatment.

EXPERT PICKS: WHAT TO READ NEXT

• About AFib: Multaq is approved to treat atrial fibrillation (AFib). Learn more about AFib, including the different types and what may trigger it.

• Possible side effects: Find out more about Multaq’s side effects — from diarrhea to fatigue — and how to manage them.

• Other AFib medications: People taking Multaq usually also take a blood thinner to help prevent a stroke due to AFib. Read about the blood thinners prescribed for AFib and why some are preferred over others.

Are there any dosage adjustments for health conditions?

No. The manufacturer doesn’t recommend Multaq dosage adjustments for people with certain health conditions. People with kidney disease and mild or moderate liver disease should take the standard Multaq dosage described above.

However, your cardiologist (heart specialist) may avoid prescribing this medication if you have severe liver disease. Multaq wasn’t studied in people with severe liver problems. So the manufacturer couldn’t accurately determine an appropriate dosage for this population. And Multaq has been linked to liver injury in rare cases.

Multaq also has a number of drug interactions to keep in mind. In some cases, it could be dangerous to combine certain medications with Multaq. It’s a good idea to let your healthcare team know about any medications you take, including over-the-counter medications and herbal supplements. An updated medication list is a great tool for your healthcare team to help you avoid interactions.

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What happens if you miss a dose of Multaq?

If you miss a dose of Multaq, take your next dose at its regularly scheduled time. Don’t double the dose to make up for a missed one. This could raise your risk of side effects. Let your cardiology care team know if you’ve missed several doses in a row. They may want to see you in person to check your heart rhythm.

If you find yourself forgetting Multaq doses frequently, consider setting a reminder on your phone or on a calendar. Medication reminder apps, such as GoodRx’s Medicine Cabinet, are great tools to help keep you on track. Many are available for free to download on a smartphone.

What should you do if you take too much Multaq?

If you take too much Multaq, contact your cardiology care team right away. They may want to evaluate you in person, depending on how much Multaq you took. You can also contact Poison Control at 1-800-222-1222 if you’re unable to reach your cardiologist’s office. If you have any symptoms that seem severe or life-threatening, call 911 or go to your nearest ER.

Taking more Multaq than recommended can raise the risk of side effects. These could be mild, such as diarrhea or upset stomach. But more serious side effects, such as abnormal heart rhythms, are also possible.

How to save on Multaq

There are ways to save on Multaq, which is only available as a brand-name medication. GoodRx can help you navigate between patient assistance programs and copay savings cards to save money on your prescription.

• Save with a copay savings card. If you have commercial insurance, you may be eligible to pay as little as $0 per prescription for Multaq using a savings card from the manufacturer.

• Save with patient assistance programs. If you’re uninsured or underinsured, you may be eligible for Multaq’s patient assistance program, which offers the medication free of cost.

Why trust our experts?

Written by:

Sarah Morin, RPh

Sarah Morin, RPh, has been a registered pharmacist for over 25 years. She started out as a hospital pharmacist, working at Rhode Island Hospital and then at the University of Connecticut Health Center.

Edited by:

Christina Aungst, PharmD

Christina Aungst, PharmD, is a pharmacy editor for GoodRx. She began writing for GoodRx Health in 2019, transitioning from freelance writer to editor in 2021.

Reviewed by:

Austin Ulrich, PharmD, BCACP

Austin Ulrich, PharmD, BCACP, is a board-certified ambulatory care clinical pharmacist. In his early career, he provided direct patient care in a variety of settings, including hospital and community pharmacies, and in a primary care clinic as a clinical pharmacist.

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