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Compare Lasix vs. Eplerenone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Furosemide (Lasix) and eplerenone (Inspra) are both medications used to treat high blood pressure, but they belong to different medication classes. Furosemide is a loop diuretic, which helps your body get rid of extra water and electrolytes, while eplerenone is an aldosterone receptor antagonist that blocks a hormone to lower blood pressure. Furosemide is also used to treat swelling (edema) due to heart, liver, or kidney problems, whereas eplerenone is used to improve survival in people with heart failure after a heart attack. Furosemide is available as a tablet or oral solution and is typically taken once or twice daily, while eplerenone is taken as a tablet once or twice daily. Both medications are available in generic forms. Common side effects of furosemide include increased urination and dizziness, while eplerenone can cause digestive issues and high potassium levels. Furosemide may interact with medications like corticosteroids, while eplerenone can interact with ACE inhibitors and NSAIDs, increasing the risk of high potassium levels.

  • Furosemide (Lasix)
    Eplerenone (Inspra)
  • Furosemide (Lasix)
    Eplerenone (Inspra)

  • Summary of Lasix vs. Eplerenone

    Summary for Diuretic (water pill)
    Prescription only

    Furosemide (Lasix) is a loop diuretic, a type of water pill. Furosemide (Lasix) is used to relieve swelling from extra fluids in children and adults. This medication can also lower blood pressure, though it's not a first-choice option for this condition. Furosemide (Lasix) comes as a tablet that's taken by mouth, typically once or twice daily. It's also available as an oral solution for people who've trouble swallowing tablets. Furosemide (Lasix) will cause you to urinate more often as a side effect, so it's best to not take this medication too close to bedtime.

    Summary for Aldosterone receptor antagonist
    Prescription only

    Eplerenone (Inspra) is a medication that’s used to treat high blood pressure and improve survival among people with heart failure after a heart attack. It comes as an oral tablet that can be taken alone or in combination with other medications. Look out for side effects including dizziness, nausea, cough, and shortness of breath. Eplerenone (Inspra) is available as a generic tablet and also under the brand name Inspra.

  • Indications of Lasix vs. Eplerenone

    Indications for
    •Swelling (edema) due to heart failure, liver problems, or kidney problems
    •High blood pressure
    Indications for
    •Heart failure after a heart attack
    •High blood pressure

  • Pros and Cons of Lasix vs. Eplerenone

    Pros and Const for Diuretic (water pill)
    Pros
    •Starts working within an hour after you take it
    •Available in liquid form for children or people who have trouble swallowing pills
    •Available as a lower-cost generic medication
    Cons
    •Not a good choice for people with a sulfa allergy
    •Might cause you to urinate in the middle of the night if you take it later in the day
    •Can make you more dizzy and raise your risk for falling down
    Pros and Const for Aldosterone receptor antagonist
    Pros
    •Improves survival for people with heart failure after a heart attack
    •Fewer side effects than spironolactone
    •Typically once daily dosing
    Cons
    •Have to get regular blood tests while taking the medication to check for high potassium levels
    •Not safe to use with severe kidney problems
    •Isn’t a first-choice medication for high blood pressure or heart failure

  • Common Side Effects of Lasix vs. Eplerenone

    Common Side Effects for
    •Urinating more often
    •Dizziness
    •Headache
    •Feeling off balance when you get up suddenly
    •Skin sensitive to the sun
    Common Side Effects for
    •Digestive system problems (20%)
    •Nervous system problems (15%)
    •Urinary tract problems (14%)
    •Shortness of breath (7%)
    •Skin problems (7%)
    •Mental health problems (7%)
    •Cough (5%)

  • Warnings of Lasix vs. Eplerenone

    Common Side Effects for
    •Dehydration and electrolyte imbalance
    •Caution in people with liver problems
    •Hearing problems
    •Problems with urination
    •Allergic reaction
    •Gout
    Common Side Effects for
    •High potassium (hyperkalemia)

  • Prices with our coupons for Lasix vs. Eplerenone

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    Learn more about Eplerenone

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