Head-to-head comparisons of medication uses, side effects, warnings, and more.
Humulin R (insulin regular) and Actos (pioglitazone) are both used to manage diabetes, but they belong to different medication classes and work in different ways. Humulin R is a short-acting insulin that helps control blood sugar by allowing your body to absorb and store sugar after meals. It is available in two strengths, U-100 and U-500, and is typically injected under the skin multiple times a day. Actos, on the other hand, is a thiazolidinedione taken orally once a day. It helps your body respond better to insulin and lowers the amount of sugar your liver makes. While Humulin R can be used for both Type 1 and Type 2 diabetes, Actos is only approved for Type 2 diabetes. Humulin R is available over the counter in its U-100 form, whereas Actos requires a prescription. Common side effects of Humulin R include low blood sugar and injection site reactions, while Actos can cause weight gain, swelling, and may worsen heart failure. Additionally, Actos has a generic version available, which can be more cost-effective.
Novolin N, a brand name of insulin NPH, is an intermediate-acting insulin. It helps control blood sugar levels in adults and children with Type 1 diabetes or Type 2 diabetes. This type of insulin comes in a vial (Novolin N) and a pen (Novolin N Flexpen). There's also a Novolin N ReliOn brand name. Novolin N is injected under the skin once or twice daily to regulate blood sugar levels. Side effects include low blood sugar (hypoglycemia) and reactions at the injection site.
Pioglitazone (Actos) is an oral medication used to treat Type 2 diabetes in adults, along with diet and exercise. It's a thiazolidinedione, which works by helping your body respond better to insulin. This medication is taken by mouth once a day and is available in both brand and generic forms. Side effects include headache, swelling in the body, and weight gain. There's also a serious warning that it can cause or worsen heart failure.
Side effects above are for pioglitazone (Actos) taken alone. These might differ if it's taken with other medications.
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